Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker

BACKGROUND: The molecular pathogenesis of T-cell large granular lymphocytic leukemia (T-LGLL), a mature T-cell leukemia arising commonly from T-cell receptor αβ-positive CD8(+) memory cytotoxic T cells, is only partly understood. The role of deregulated methylation in T-LGLL is not well known. We an...

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Detalles Bibliográficos
Autores principales: Johansson, Patricia, Laguna, Teresa, Ossowski, Julio, Pancaldi, Vera, Brauser, Martina, Dührsen, Ulrich, Keuneke, Lara, Queiros, Ana, Richter, Julia, Martín-Subero, José I., Siebert, Reiner, Schlegelberger, Brigitte, Küppers, Ralf, Dürig, Jan, Murga Penas, Eva M., Carillo-de Santa Pau, Enrique, Bergmann, Anke K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664638/
https://www.ncbi.nlm.nih.gov/pubmed/36376973
http://dx.doi.org/10.1186/s13148-022-01362-z

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