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Preclinical evaluation of combination nemtabrutinib and venetoclax in chronic lymphocytic leukemia
Inhibitors of B cell receptor (BCR) signaling such as the Bruton’s tyrosine kinase (BTK) inhibitors are effective therapeutics for chronic lymphocytic leukemia (CLL). The first-in-class covalent BTK inhibitor, ibrutinib, produces durable responses in most CLL patients; however, complete responses ar...
Autores principales: | Muhowski, Elizabeth M., Ravikrishnan, Janani, Gordon, Britten, Yu, Lianbo, Misra, Shrilekha, Walker, Brandi, Eathiraj, Sudharshan, Sampath, Deepa, Rogers, Kerry A., Byrd, John C., Woyach, Jennifer A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664697/ https://www.ncbi.nlm.nih.gov/pubmed/36380319 http://dx.doi.org/10.1186/s13045-022-01386-1 |
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