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Single sample pathway analysis in metabolomics: performance evaluation and application

BACKGROUND: Single sample pathway analysis (ssPA) transforms molecular level omics data to the pathway level, enabling the discovery of patient-specific pathway signatures. Compared to conventional pathway analysis, ssPA overcomes the limitations by enabling multi-group comparisons, alongside facili...

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Detalles Bibliográficos
Autores principales: Wieder, Cecilia, Lai, Rachel P. J., Ebbels, Timothy M. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664704/
https://www.ncbi.nlm.nih.gov/pubmed/36376837
http://dx.doi.org/10.1186/s12859-022-05005-1