Hepatitis B virus suppresses complement C9 synthesis by limiting the availability of transcription factor USF-1 and inhibits formation of membrane attack complex: implications in disease pathogenesis

BACKGROUND: The complement system functions primarily as a first-line host defense against invading microbes, including viruses. However, the interaction of Hepatitis B virus (HBV) with the complement-components during chronic HBV infection remains largely unknown. We investigated the mechanism by w...

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Detalles Bibliográficos
Autores principales: Baidya, Ayana, Khatun, Mousumi, Mondal, Rajiv Kumar, Ghosh, Suchandrima, Chakraborty, Bidhan Chandra, Mallik, Shreya, Ahammed, S. K. Mahiuddin, Chowdhury, Abhijit, Banerjee, Soma, Datta, Simanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664717/
https://www.ncbi.nlm.nih.gov/pubmed/36376872
http://dx.doi.org/10.1186/s12929-022-00876-1

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