Potential use of EGFR-targeted molecular therapies for tumor suppressor CYLD-negative and poor prognosis oral squamous cell carcinoma with chemoresistance

BACKGROUND: Tumor suppressor CYLD dysfunction by loss of its expression, triggers malignant transformation, especially drug resistance and tumor invasion/metastasis. Although loss of CYLD expression is significantly associated with poor prognosis in a large variety of tumors, no clinically-effective...

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Detalles Bibliográficos
Autores principales: Kanemaru, Ayumi, Shinriki, Satoru, Kai, Mimi, Tsurekawa, Kanae, Ozeki, Kazuya, Uchino, Shota, Suenaga, Naoki, Yonemaru, Kou, Miyake, Shunsuke, Masuda, Takeshi, Kariya, Ryusho, Okada, Seiji, Takeshita, Hisashi, Seki, Yuki, Yano, Hiromu, Komohara, Yoshihiro, Yoshida, Ryoji, Nakayama, Hideki, Li, Jian-Dong, Saito, Hideyuki, Jono, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664721/
https://www.ncbi.nlm.nih.gov/pubmed/36376983
http://dx.doi.org/10.1186/s12935-022-02781-x

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