HER2 amplification by next-generation sequencing to identify HER2-positive invasive breast cancer with negative HER2 immunohistochemistry

BACKGROUND: Human epidermal growth factor receptor 2 (HER2) positive breast carcinomas due to HER2 amplification are associated with aggressive behavior and a poor prognosis. Anti-HER2-targeted therapies are widely used to treat HER2-positive breast carcinomas with excellent outcomes. Accurate ident...

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Detalles Bibliográficos
Autores principales: Morsberger, Laura, Pallavajjala, Aparna, Long, Patty, Hardy, Melanie, Park, Rebecca, Parish, Rebecca, Nozari, Azin, Zou, Ying S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664724/
https://www.ncbi.nlm.nih.gov/pubmed/36376842
http://dx.doi.org/10.1186/s12935-022-02761-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664724/
https://www.ncbi.nlm.nih.gov/pubmed/36376842
http://dx.doi.org/10.1186/s12935-022-02761-1

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