PHLPP isoforms differentially regulate Akt isoforms and AS160 affecting neuronal insulin signaling and insulin resistance via Scribble

BACKGROUND: The aim of the present study was to determine the role of individual PHLPP isoforms in insulin signaling and insulin resistance in neuronal cells. METHODS: PHLPP isoforms were either silenced or overexpressed individually, and the effects were observed on individual Akt isoforms, AS160 a...

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Detalles Bibliográficos
Autores principales: Sharma, Medha, Dey, Chinmoy Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664818/
https://www.ncbi.nlm.nih.gov/pubmed/36376971
http://dx.doi.org/10.1186/s12964-022-00987-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664818/
https://www.ncbi.nlm.nih.gov/pubmed/36376971
http://dx.doi.org/10.1186/s12964-022-00987-0

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