Neuroinflammation regulates the balance between hippocampal neuron death and neurogenesis in an ex vivo model of thiamine deficiency

BACKGROUND: Thiamine (vitamin B1) is a cofactor for enzymes of central energy metabolism and its deficiency (TD) impairs oxidative phosphorylation, increases oxidative stress, and activates inflammatory processes that can lead to neurodegeneration. Wernicke–Korsakoff syndrome (WKS) is a consequence...

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Detalles Bibliográficos
Autores principales: Cassiano, Larissa M. G., Oliveira, Marina S., Pioline, Jeanne, Salim, Anna C. M., Coimbra, Roney S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664832/
https://www.ncbi.nlm.nih.gov/pubmed/36376954
http://dx.doi.org/10.1186/s12974-022-02624-6

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