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New In Vitro Interaction-Parasite Reduction Ratio Assay for Early Derisk in Clinical Development of Antimalarial Combinations
The development and spread of drug-resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but require intensive preclinical studies to determine optimal combination and dosing regimens. To support t...
Autores principales: | Wicha, Sebastian G., Walz, Annabelle, Cherkaoui-Rbati, Mohammed H., Bundgaard, Nils, Kuritz, Karsten, Gumpp, Christin, Gobeau, Nathalie, Möhrle, Jörg, Rottmann, Matthias, Demarta-Gatsi, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664866/ https://www.ncbi.nlm.nih.gov/pubmed/36197116 http://dx.doi.org/10.1128/aac.00556-22 |
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