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Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis

Obesity perturbs central functions of human adipose tissue, centred on differentiation of preadipocytes to adipocytes, i.e., adipogenesis. The large environmental component of obesity makes it important to elucidate epigenetic regulatory factors impacting adipogenesis. Promoter Capture Hi-C (pCHi-C)...

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Detalles Bibliográficos
Autores principales: Garske, Kristina M., Comenho, Caroline, Pan, David Z., Alvarez, Marcus, Mohlke, Karen, Laakso, Markku, Pietiläinen, Kirsi H., Pajukanta, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665133/
https://www.ncbi.nlm.nih.gov/pubmed/35746833
http://dx.doi.org/10.1080/15592294.2022.2088145