Cargando…
Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis
Obesity perturbs central functions of human adipose tissue, centred on differentiation of preadipocytes to adipocytes, i.e., adipogenesis. The large environmental component of obesity makes it important to elucidate epigenetic regulatory factors impacting adipogenesis. Promoter Capture Hi-C (pCHi-C)...
Autores principales: | Garske, Kristina M., Comenho, Caroline, Pan, David Z., Alvarez, Marcus, Mohlke, Karen, Laakso, Markku, Pietiläinen, Kirsi H., Pajukanta, Päivi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665133/ https://www.ncbi.nlm.nih.gov/pubmed/35746833 http://dx.doi.org/10.1080/15592294.2022.2088145 |
Ejemplares similares
-
Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans
por: Garske, Kristina M., et al.
Publicado: (2019) -
Correction to: Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes
por: Pan, David Z., et al.
Publicado: (2021) -
Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes
por: Pan, David Z., et al.
Publicado: (2021) -
Increased body mass index is linked to systemic inflammation through altered chromatin co-accessibility in human preadipocytes
por: Garske, Kristina M., et al.
Publicado: (2023) -
Publisher Correction: Accurate estimation of cell composition in bulk expression through robust integration of single-cell information
por: Jew, Brandon, et al.
Publicado: (2020)