The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip

DNA methylation (DNAm) is commonly assayed using the Illumina Infinium MethylationEPIC BeadChip, but there is currently little published evidence to define the lower limits of the amount of DNA that can be used whilst preserving data quality. Such evidence is valuable for analyses utilizing precious...

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Detalles Bibliográficos
Autores principales: Watkins, Sarah Holmes, Ho, Karen, Testa, Christian, Falk, Louise, Soule, Patrice, Nguyen, Linda V., FitzGibbon, Sophie, Slack, Catherine, Chen, Jarvis T., Davey Smith, George, De Vivo, Immaculata, Simpkin, Andrew J., Tilling, Kate, Waterman, Pamela D., Krieger, Nancy, Suderman, Matthew, Relton, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665153/
https://www.ncbi.nlm.nih.gov/pubmed/36239035
http://dx.doi.org/10.1080/15592294.2022.2123898

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