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Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals

Despite the overwhelming success of mRNA-based vaccine in protecting against SARS-CoV-2 infection and reducing disease severity and hospitalization, little is known about the role lipid nanoparticles (LNP) play in initiating immune response. In this report we studied the adjuvantive impact of empty...

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Detalles Bibliográficos
Autores principales: Connors, Jennifer, Joyner, David, Mege, Nathan, Cusimano, Gina, Bell, Matthew, Marcy, Jennifer, Taramangalam, Bhavani, Lin, Paulo, Tam, Ying, Weissman, Drew, Kutzler, Michele, Alameh, Mohamad-Gabriel, Haddad, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665340/
https://www.ncbi.nlm.nih.gov/pubmed/36380763
http://dx.doi.org/10.21203/rs.3.rs-2199652/v1