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Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals
Despite the overwhelming success of mRNA-based vaccine in protecting against SARS-CoV-2 infection and reducing disease severity and hospitalization, little is known about the role lipid nanoparticles (LNP) play in initiating immune response. In this report we studied the adjuvantive impact of empty...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665340/ https://www.ncbi.nlm.nih.gov/pubmed/36380763 http://dx.doi.org/10.21203/rs.3.rs-2199652/v1 |
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por Connors, Jennifer, Joyner, David, Mege, Nathan J., Cusimano, Gina M., Bell, Matthew R., Marcy, Jennifer, Taramangalam, Bhavani, Kim, Kenneth M., Lin, Paulo J. C., Tam, Ying K., Weissman, Drew, Kutzler, Michele A., Alameh, Mohamad-Gabriel, Haddad, Elias K.
Publicado 2023
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Publicado 2023
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Online
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Texto