In vitro methods to ensure absence of residual undifferentiated human induced pluripotent stem cells intermingled in induced nephron progenitor cells

Cell therapies using human induced pluripotent stem cell (hiPSC)-derived nephron progenitor cells (NPCs) are expected to ameliorate acute kidney injury (AKI). However, using hiPSC-derived NPCs clinically is a challenge because hiPSCs themselves are tumorigenic. LIN28A, ESRG, CNMD and SFRP2 transcrip...

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Detalles Bibliográficos
Autores principales: Tsujimoto, Hiraku, Katagiri, Naoko, Ijiri, Yoshihiro, Sasaki, Ben, Kobayashi, Yoshifumi, Mima, Akira, Ryosaka, Makoto, Furuyama, Kenichiro, Kawaguchi, Yoshiya, Osafune, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665373/
https://www.ncbi.nlm.nih.gov/pubmed/36378656
http://dx.doi.org/10.1371/journal.pone.0275600

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