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Improvement of non-invasive tests of liver steatosis and fibrosis as indicators for non-alcoholic fatty liver disease in type 2 diabetes mellitus patients with elevated cardiovascular risk profile using the PPAR-α/γ agonist aleglitazar
BACKGROUND: Peroxisome proliferator-activated receptor (PPAR) agonists may have favorable outcomes on non-alcoholic fatty liver disease. This study serves as proof of concept to evaluate whether dual PPAR-α/γ agonists improve non-invasive tests of liver steatosis and fibrosis. METHODS: This is a pos...
Autores principales: | Grobbee, Esmée J., de Jong, Vivian D., Schrieks, Ilse C., Tushuizen, Maarten E., Holleboom, Adriaan G., Tardif, Jean-Claude, Lincoff, A. Michael, Schwartz, Gregory G., Castro Cabezas, Manuel, Grobbee, Diederick E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665379/ https://www.ncbi.nlm.nih.gov/pubmed/36378671 http://dx.doi.org/10.1371/journal.pone.0277706 |
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