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SCAFE: a software suite for analysis of transcribed cis-regulatory elements in single cells
MOTIVATION: Cell type-specific activities of cis-regulatory elements (CRE) are central to understanding gene regulation and disease predisposition. Single-cell RNA 5′end sequencing (sc-end5-seq) captures the transcription start sites (TSS) which can be used as a proxy to measure the activity of tran...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665856/ https://www.ncbi.nlm.nih.gov/pubmed/36173306 http://dx.doi.org/10.1093/bioinformatics/btac644 |