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SCAFE: a software suite for analysis of transcribed cis-regulatory elements in single cells

MOTIVATION: Cell type-specific activities of cis-regulatory elements (CRE) are central to understanding gene regulation and disease predisposition. Single-cell RNA 5′end sequencing (sc-end5-seq) captures the transcription start sites (TSS) which can be used as a proxy to measure the activity of tran...

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Detalles Bibliográficos
Autores principales: Moody, Jonathan, Kouno, Tsukasa, Chang, Jen-Chien, Ando, Yoshinari, Carninci, Piero, Shin, Jay W, Hon, Chung-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665856/
https://www.ncbi.nlm.nih.gov/pubmed/36173306
http://dx.doi.org/10.1093/bioinformatics/btac644