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NLRP1 activation by UVB: Shedding light on an enigmatic inflammasome
In this issue of JEM, Jenster et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20220837) investigate how UVB radiation promotes activation of the inflammatory immune sensor NLRP1, and in doing so uncover how NLRP1 recognizes a diverse range of ribotoxic stresses.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665900/ https://www.ncbi.nlm.nih.gov/pubmed/36374226 http://dx.doi.org/10.1084/jem.20221720 |
Sumario: | In this issue of JEM, Jenster et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20220837) investigate how UVB radiation promotes activation of the inflammatory immune sensor NLRP1, and in doing so uncover how NLRP1 recognizes a diverse range of ribotoxic stresses. |
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