Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report

Sister Mary Joseph’s nodules (SMJNs) are umbilical skin metastases of various abdominopelvic malignancies, and they rarely originate from renal cell carcinomas. Radiotherapy is typically used to treat the nodules as a palliative intention. We report a rare case of SMJN that originated from clear cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Hirata, Kimiko, Narabayashi, Masaru, Murashima, Takaya, Segawa, Takehiko, Ohtsu, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Radiation Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665911/
https://www.ncbi.nlm.nih.gov/pubmed/36407130
http://dx.doi.org/10.7759/cureus.30344
_version_ 1784831389073408000
author Hirata, Kimiko
Narabayashi, Masaru
Murashima, Takaya
Segawa, Takehiko
Ohtsu, Shuji
author_facet Hirata, Kimiko
Narabayashi, Masaru
Murashima, Takaya
Segawa, Takehiko
Ohtsu, Shuji
author_sort Hirata, Kimiko
collection PubMed
description Sister Mary Joseph’s nodules (SMJNs) are umbilical skin metastases of various abdominopelvic malignancies, and they rarely originate from renal cell carcinomas. Radiotherapy is typically used to treat the nodules as a palliative intention. We report a rare case of SMJN that originated from clear cell renal cell carcinoma, which was treated with external beam radiation therapy (EBRT) and interstitial brachytherapy (ISBT). A 74-year-old male patient with a history of left renal cell carcinoma developed an umbilical nodule which was diagnosed as SMJN. The patient underwent EBRT (30 Gy in 10 fractions) and ISBT (12 Gy in two fractions), leading the nodule to complete resolution. This case report might support that radiotherapy, including ISBT, is effective for the treatment of SMJN from renal cell carcinoma.
format Online
Article
Text
id pubmed-9665911
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-96659112022-11-17 Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report Hirata, Kimiko Narabayashi, Masaru Murashima, Takaya Segawa, Takehiko Ohtsu, Shuji Cureus Radiation Oncology Sister Mary Joseph’s nodules (SMJNs) are umbilical skin metastases of various abdominopelvic malignancies, and they rarely originate from renal cell carcinomas. Radiotherapy is typically used to treat the nodules as a palliative intention. We report a rare case of SMJN that originated from clear cell renal cell carcinoma, which was treated with external beam radiation therapy (EBRT) and interstitial brachytherapy (ISBT). A 74-year-old male patient with a history of left renal cell carcinoma developed an umbilical nodule which was diagnosed as SMJN. The patient underwent EBRT (30 Gy in 10 fractions) and ISBT (12 Gy in two fractions), leading the nodule to complete resolution. This case report might support that radiotherapy, including ISBT, is effective for the treatment of SMJN from renal cell carcinoma. Cureus 2022-10-16 /pmc/articles/PMC9665911/ /pubmed/36407130 http://dx.doi.org/10.7759/cureus.30344 Text en Copyright © 2022, Hirata et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiation Oncology
Hirata, Kimiko
Narabayashi, Masaru
Murashima, Takaya
Segawa, Takehiko
Ohtsu, Shuji
Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report
title Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report
title_full Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report
title_fullStr Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report
title_full_unstemmed Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report
title_short Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report
title_sort sister mary joseph's nodule from renal cell carcinoma: a case report
topic Radiation Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9665911/
https://www.ncbi.nlm.nih.gov/pubmed/36407130
http://dx.doi.org/10.7759/cureus.30344
work_keys_str_mv AT hiratakimiko sistermaryjosephsnodulefromrenalcellcarcinomaacasereport
AT narabayashimasaru sistermaryjosephsnodulefromrenalcellcarcinomaacasereport
AT murashimatakaya sistermaryjosephsnodulefromrenalcellcarcinomaacasereport
AT segawatakehiko sistermaryjosephsnodulefromrenalcellcarcinomaacasereport
AT ohtsushuji sistermaryjosephsnodulefromrenalcellcarcinomaacasereport

Ejemplares similares