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Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury

BACKGROUND: Ferroptosis plays a key role in cardiomyopathy. Atorvastatin (ATV) has a protective effect on ischemia-reperfusion (I/R) cardiomyopathy. The purpose of this study is to elucidate the mechanism of ATV in I/R injury. METHODS: H9C2 cells and cardiomyopathy rats were induced by hypoxia/reoxy...

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Detalles Bibliográficos
Autores principales: Peng, You, Liao, Bin, Zhou, Yan, Zeng, Wei, Zeng, Zhi-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666047/
https://www.ncbi.nlm.nih.gov/pubmed/36398315
http://dx.doi.org/10.1155/2022/3972829

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