Cargando…
Low-grade myofibroblastic sarcoma of the proximal femur: A case report and literature review
Low-grade myofibroblastic sarcoma (LGMS) is an atypical type of tumor composed of myofibroblasts. LGMS in the femoral head neck junction is extremely rare and no case treated by hip arthroscopy was reported. PATIENT CONCERNS: We reported a case of LGMS in the femoral head neck junction treated by hi...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666109/ https://www.ncbi.nlm.nih.gov/pubmed/36397412 http://dx.doi.org/10.1097/MD.0000000000031715 |
_version_ | 1784831429509644288 |
---|---|
author | Gao, Guanying Liu, Yuhao Ao, Yingfang Wang, Jianquan Xu, Yan |
author_facet | Gao, Guanying Liu, Yuhao Ao, Yingfang Wang, Jianquan Xu, Yan |
author_sort | Gao, Guanying |
collection | PubMed |
description | Low-grade myofibroblastic sarcoma (LGMS) is an atypical type of tumor composed of myofibroblasts. LGMS in the femoral head neck junction is extremely rare and no case treated by hip arthroscopy was reported. PATIENT CONCERNS: We reported a case of LGMS in the femoral head neck junction treated by hip arthroscopy. A 30-year-old female was admitted to our hospital with discomfort and pain after left hip sprained one year prior. Physical examination revealed swelling of the left hip and magnetic resonance images showed a soft tissue mass in the femoral head neck junction. DIAGNOSIS: Via microscopy of pathological specimens, spindle cell proliferative lesions, atypia of some cells, and mitotic figures/pathological mitotic figures of some cells were observed. Immunohistochemistry revealed positive for smooth muscle actin, focally positive for CD34 and CD68, while negative for S-100, desmin, and anaplastic lymphoma kinase. The imaging, histomorphological and immunohistochemical features suggested a final diagnosis of LGMS of the proximal femur. INTERVENTIONS: This patient underwent hip arthroscopy for excision of the soft tissue mass. OUTCOMES: The clinical and imaging follow-up at 6 months postoperatively showed that surgery had achieved good clinical outcomes. LESSONS: To the best of our knowledge, this is the first case report of LGMS in the femoral head neck junction treated by hip arthroscopy. Beyond the present case, other 120 cases from 58 literatures (1998–2022) are reviewed and discussed. The age of LGMS patients ranged from 11 months to 77 years and the male-to-female ratio was approximately 1.28:1. The location distribution of previously reported LGMS cases and the present case was as follows: Head&neck (45.90%), trunk (30.33%), and extremity (23.77%). Hip arthroscopic excision of LGMS may achieve relatively good clinical outcomes. |
format | Online Article Text |
id | pubmed-9666109 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-96661092022-11-16 Low-grade myofibroblastic sarcoma of the proximal femur: A case report and literature review Gao, Guanying Liu, Yuhao Ao, Yingfang Wang, Jianquan Xu, Yan Medicine (Baltimore) 7100 Low-grade myofibroblastic sarcoma (LGMS) is an atypical type of tumor composed of myofibroblasts. LGMS in the femoral head neck junction is extremely rare and no case treated by hip arthroscopy was reported. PATIENT CONCERNS: We reported a case of LGMS in the femoral head neck junction treated by hip arthroscopy. A 30-year-old female was admitted to our hospital with discomfort and pain after left hip sprained one year prior. Physical examination revealed swelling of the left hip and magnetic resonance images showed a soft tissue mass in the femoral head neck junction. DIAGNOSIS: Via microscopy of pathological specimens, spindle cell proliferative lesions, atypia of some cells, and mitotic figures/pathological mitotic figures of some cells were observed. Immunohistochemistry revealed positive for smooth muscle actin, focally positive for CD34 and CD68, while negative for S-100, desmin, and anaplastic lymphoma kinase. The imaging, histomorphological and immunohistochemical features suggested a final diagnosis of LGMS of the proximal femur. INTERVENTIONS: This patient underwent hip arthroscopy for excision of the soft tissue mass. OUTCOMES: The clinical and imaging follow-up at 6 months postoperatively showed that surgery had achieved good clinical outcomes. LESSONS: To the best of our knowledge, this is the first case report of LGMS in the femoral head neck junction treated by hip arthroscopy. Beyond the present case, other 120 cases from 58 literatures (1998–2022) are reviewed and discussed. The age of LGMS patients ranged from 11 months to 77 years and the male-to-female ratio was approximately 1.28:1. The location distribution of previously reported LGMS cases and the present case was as follows: Head&neck (45.90%), trunk (30.33%), and extremity (23.77%). Hip arthroscopic excision of LGMS may achieve relatively good clinical outcomes. Lippincott Williams & Wilkins 2022-11-11 /pmc/articles/PMC9666109/ /pubmed/36397412 http://dx.doi.org/10.1097/MD.0000000000031715 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | 7100 Gao, Guanying Liu, Yuhao Ao, Yingfang Wang, Jianquan Xu, Yan Low-grade myofibroblastic sarcoma of the proximal femur: A case report and literature review |
title | Low-grade myofibroblastic sarcoma of the proximal femur: A case report and literature review |
title_full | Low-grade myofibroblastic sarcoma of the proximal femur: A case report and literature review |
title_fullStr | Low-grade myofibroblastic sarcoma of the proximal femur: A case report and literature review |
title_full_unstemmed | Low-grade myofibroblastic sarcoma of the proximal femur: A case report and literature review |
title_short | Low-grade myofibroblastic sarcoma of the proximal femur: A case report and literature review |
title_sort | low-grade myofibroblastic sarcoma of the proximal femur: a case report and literature review |
topic | 7100 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666109/ https://www.ncbi.nlm.nih.gov/pubmed/36397412 http://dx.doi.org/10.1097/MD.0000000000031715 |
work_keys_str_mv | AT gaoguanying lowgrademyofibroblasticsarcomaoftheproximalfemuracasereportandliteraturereview AT liuyuhao lowgrademyofibroblasticsarcomaoftheproximalfemuracasereportandliteraturereview AT aoyingfang lowgrademyofibroblasticsarcomaoftheproximalfemuracasereportandliteraturereview AT wangjianquan lowgrademyofibroblasticsarcomaoftheproximalfemuracasereportandliteraturereview AT xuyan lowgrademyofibroblasticsarcomaoftheproximalfemuracasereportandliteraturereview |