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The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis

A narrowed sacroiliac joint (SIJ) space has been considered to be a major morphologic parameter of ankylosing spondylitis (AS). Previous studies revealed that the sacroiliac joint thickness (SIJT) correlated with AS in patients. However, irregular narrowing is different from thickness. Thus, we devi...

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Autores principales: Bang, Yun-Sic, Hwang, He Won, Bae, Hanwool, Choi, Young-Soon, Lim, Youngsu, Yi, Jungmin, Kim, Hyunhae, Su, Min-Ying, Kim, Young Uk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666185/
https://www.ncbi.nlm.nih.gov/pubmed/36397357
http://dx.doi.org/10.1097/MD.0000000000031723
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author Bang, Yun-Sic
Hwang, He Won
Bae, Hanwool
Choi, Young-Soon
Lim, Youngsu
Yi, Jungmin
Kim, Hyunhae
Su, Min-Ying
Kim, Young Uk
author_facet Bang, Yun-Sic
Hwang, He Won
Bae, Hanwool
Choi, Young-Soon
Lim, Youngsu
Yi, Jungmin
Kim, Hyunhae
Su, Min-Ying
Kim, Young Uk
author_sort Bang, Yun-Sic
collection PubMed
description A narrowed sacroiliac joint (SIJ) space has been considered to be a major morphologic parameter of ankylosing spondylitis (AS). Previous studies revealed that the sacroiliac joint thickness (SIJT) correlated with AS in patients. However, irregular narrowing is different from thickness. Thus, we devised a method using the sacroiliac joint cross-sectional area (SIJA) as a new morphological parameter for use in evaluating AS. We hypothesized that the SIJA is a key morphologic parameter in diagnosing AS. SIJ samples were collected from 107 patients with AS, and from 85 control subjects who underwent SIJ-view X-rays that revealed no evidence of AS. We measured the SIJT and SIJA at the SIJ margin on X-rays using our picture archiving and communications system. The SIJT was measured at the narrowest point between the sacrum and the ilium. The SIJA was measured as the entire cross-sectional joint space area of the SIJ in the X-ray images. The average SIJT was 3.09 ± 0.61 mm in the control group, and 1.59 ± 0.52 mm in the AS group. The average SIJA was 166.74 ± 39.98 mm(2) in the control group, and 68.65 ± 24.11 mm(2) in the AS group. AS patients had significantly lower SIJT (P < .001) and SIJA (P < .001) than the control subjects. Receiver operating characteristics curve analysis showed that the best cutoff point for the SIJT was 2.33 mm, with 92.5% sensitivity, 94.1% specificity, and an area under the curve of 0.97 (95% confidence interval: 0.95–0.99). The optimal cutoff point for the SIJA was 106.19 mm(2), with 93.5% sensitivity, 95.3% specificity, and an area under the curve of 0.98 (95% confidence interval: 0.97–1.00). Although the SIJT and SIJA were both significantly associated with AS, the SIJA parameter was a more sensitive measurement. We concluded that the SIJA is an easy-to-use, fast, cheap, and useful new morphological parameter for predicting AS.
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spelling pubmed-96661852022-11-16 The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis Bang, Yun-Sic Hwang, He Won Bae, Hanwool Choi, Young-Soon Lim, Youngsu Yi, Jungmin Kim, Hyunhae Su, Min-Ying Kim, Young Uk Medicine (Baltimore) 6900 A narrowed sacroiliac joint (SIJ) space has been considered to be a major morphologic parameter of ankylosing spondylitis (AS). Previous studies revealed that the sacroiliac joint thickness (SIJT) correlated with AS in patients. However, irregular narrowing is different from thickness. Thus, we devised a method using the sacroiliac joint cross-sectional area (SIJA) as a new morphological parameter for use in evaluating AS. We hypothesized that the SIJA is a key morphologic parameter in diagnosing AS. SIJ samples were collected from 107 patients with AS, and from 85 control subjects who underwent SIJ-view X-rays that revealed no evidence of AS. We measured the SIJT and SIJA at the SIJ margin on X-rays using our picture archiving and communications system. The SIJT was measured at the narrowest point between the sacrum and the ilium. The SIJA was measured as the entire cross-sectional joint space area of the SIJ in the X-ray images. The average SIJT was 3.09 ± 0.61 mm in the control group, and 1.59 ± 0.52 mm in the AS group. The average SIJA was 166.74 ± 39.98 mm(2) in the control group, and 68.65 ± 24.11 mm(2) in the AS group. AS patients had significantly lower SIJT (P < .001) and SIJA (P < .001) than the control subjects. Receiver operating characteristics curve analysis showed that the best cutoff point for the SIJT was 2.33 mm, with 92.5% sensitivity, 94.1% specificity, and an area under the curve of 0.97 (95% confidence interval: 0.95–0.99). The optimal cutoff point for the SIJA was 106.19 mm(2), with 93.5% sensitivity, 95.3% specificity, and an area under the curve of 0.98 (95% confidence interval: 0.97–1.00). Although the SIJT and SIJA were both significantly associated with AS, the SIJA parameter was a more sensitive measurement. We concluded that the SIJA is an easy-to-use, fast, cheap, and useful new morphological parameter for predicting AS. Lippincott Williams & Wilkins 2022-11-11 /pmc/articles/PMC9666185/ /pubmed/36397357 http://dx.doi.org/10.1097/MD.0000000000031723 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 6900
Bang, Yun-Sic
Hwang, He Won
Bae, Hanwool
Choi, Young-Soon
Lim, Youngsu
Yi, Jungmin
Kim, Hyunhae
Su, Min-Ying
Kim, Young Uk
The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis
title The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis
title_full The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis
title_fullStr The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis
title_full_unstemmed The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis
title_short The value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis
title_sort value of the sacroiliac joint area as a new morphological parameter of ankylosing spondylitis
topic 6900
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666185/
https://www.ncbi.nlm.nih.gov/pubmed/36397357
http://dx.doi.org/10.1097/MD.0000000000031723
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