ECM1 regulates the resistance of colorectal cancer to 5-FU treatment by modulating apoptotic cell death and epithelial-mesenchymal transition induction

5-Fluorouracil (5-FU) chemoresistance is a persistent impediment to the efficient treatment of many types of cancer, yet the molecular mechanisms underlying such resistance remain incompletely understood. Here we found CRC patients resistant to 5-FU treatment exhibited increased extracellular matrix...

Descripción completa

Detalles Bibliográficos
Autores principales: Long, Sirui, Wang, Jie, Weng, Fanbin, Pei, Zhigang, Zhou, Shixian, Sun, Guiyin, Xiang, Debing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666402/
https://www.ncbi.nlm.nih.gov/pubmed/36408224
http://dx.doi.org/10.3389/fphar.2022.1005915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666402/
https://www.ncbi.nlm.nih.gov/pubmed/36408224
http://dx.doi.org/10.3389/fphar.2022.1005915

Ejemplares similares