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ECM1 regulates the resistance of colorectal cancer to 5-FU treatment by modulating apoptotic cell death and epithelial-mesenchymal transition induction
5-Fluorouracil (5-FU) chemoresistance is a persistent impediment to the efficient treatment of many types of cancer, yet the molecular mechanisms underlying such resistance remain incompletely understood. Here we found CRC patients resistant to 5-FU treatment exhibited increased extracellular matrix...
Autores principales: | Long, Sirui, Wang, Jie, Weng, Fanbin, Pei, Zhigang, Zhou, Shixian, Sun, Guiyin, Xiang, Debing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666402/ https://www.ncbi.nlm.nih.gov/pubmed/36408224 http://dx.doi.org/10.3389/fphar.2022.1005915 |
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