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The molecular biology of tubulinopathies: Understanding the impact of variants on tubulin structure and microtubule regulation
Heterozygous, missense mutations in both α- and β-tubulin genes have been linked to an array of neurodevelopment disorders, commonly referred to as “tubulinopathies.” To date, tubulinopathy mutations have been identified in three β-tubulin isotypes and one α-tubulin isotype. These mutations occur th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666403/ https://www.ncbi.nlm.nih.gov/pubmed/36406756 http://dx.doi.org/10.3389/fncel.2022.1023267 |