Cargando…

Functional analysis of the short splicing variant encoded by CHI3L1/YKL-40 in glioblastoma

The glycoprotein YKL-40 has been well studied as a serum biomarker of prognosis and disease status in glioblastoma. YKL-40 is a chitinase-like protein with defective chitinase activity that plays an important role in promoting cell proliferation, migration, and metastasis in glioblastoma multiforme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Mengqi, Ge, Qianyun, Wang, Xinrong, Diao, Wenbin, Yang, Ben, Sun, Sipeng, Wang, Guohui, Liu, Tian, Chan, Andrew Man-Lok, Gao, Zhiqin, Wang, Yi, Wang, Yubing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666495/ https://www.ncbi.nlm.nih.gov/pubmed/36408158 http://dx.doi.org/10.3389/fonc.2022.910728

Ejemplares similares

Astrocyte-specific knockout of YKL-40/Chi3l1 reduces Aβ burden and restores memory functions in 5xFAD mice
por: Zeng, Xiaoyan, et al.
Publicado: (2023)

Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and Prediction of Fatal and Non-fatal Ischemic Stroke
por: Rathcke, Camilla Noelle, et al.
Publicado: (2012)

In vivo CHI3L1 (YKL-40) expression in astrocytes in acute and chronic neurological diseases
por: Bonneh-Barkay, Dafna, et al.
Publicado: (2010)

PNA-Modified Liposomes Improve the Delivery Efficacy of CAPIRI for the Synergistic Treatment of Colorectal Cancer
por: Diao, Wenbin, et al.
Publicado: (2022)

Vascular heterogeneity and targeting: the role of YKL-40 in glioblastoma vascularization
por: Shao, Rong, et al.
Publicado: (2015)

YKL-40 and genetic status of CHI3L1 in a large group of asthmatics
por: Hansen, Jakob W., et al.
Publicado: (2015)

The Association between Genetic Variations of CHI3L1, Levels of the Encoded Glycoprotein YKL-40 and the Lipid Profile in a Danish Population
por: Thomsen, Stine Brinkløv, et al.
Publicado: (2012)

The different role of YKL-40 in glioblastoma is a function of MGMT promoter methylation status
por: Chen, Wei-jun, et al.
Publicado: (2020)

Unveiling YKL-40, from Serum Marker to Target Therapy in Glioblastoma
por: Iwamoto, Fabio M., et al.
Publicado: (2014)

Perspective: targeting VEGF-A and YKL-40 in glioblastoma – matter matters
por: Holst, Camilla Bjørnbak, et al.
Publicado: (2021)

CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development
por: Usemann, Jakob, et al.
Publicado: (2016)

TrkB-containing exosomes promote the transfer of glioblastoma aggressiveness to YKL-40-inactivated glioblastoma cells
por: Pinet, Sandra, et al.
Publicado: (2016)

Serum YKL-40 and colorectal cancer
por: Cintin, C, et al.
Publicado: (1999)

YKL-40 correlates with the phenotype of asthma
por: Specjalski, Krzysztof, et al.
Publicado: (2015)

Chitinase-3-like 1 protein (CHI3L1) locus influences cerebrospinal fluid levels of YKL-40
por: Deming, Yuetiva, et al.
Publicado: (2016)

Systemic Immune Modulation in Gliomas: Prognostic Value of Plasma IL-6, YKL-40, and Genetic Variation in YKL-40
por: Holst, Camilla Bjørnbak, et al.
Publicado: (2020)

Association of CHI3L1 gene variants with YKL‐40 levels and hypertension incidence: A population‐based nested case‐control study in China
por: Xu, Tian, et al.
Publicado: (2020)

YKL-40 Protein Correlates with the Phenotype of Asthma
por: Specjalski, Krzysztof, et al.
Publicado: (2015)

Plasma YKL-40 in the spectrum of neurodegenerative dementia
por: Villar-Piqué, Anna, et al.
Publicado: (2019)

Increased immunohistochemical expression of YKL-40 in the spleen of patients with portal hypertension
por: Wang, Dong, et al.
Publicado: (2012)

Association of Circulating YKL-40 Levels and CHI3L1 Variants with the Risk of Spinal Deformity Progression in Adolescent Idiopathic Scoliosis
por: Nada, Dina, et al.
Publicado: (2019)

Elevated YKL-40 expression is associated with a poor prognosis in breast cancer patients
por: Wan, Guoxing, et al.
Publicado: (2016)

CTX-II and YKL-40 in early diagnosis and treatment evaluation of osteoarthritis
por: Wang, Pengkun, et al.
Publicado: (2019)

YKL-40 Is Associated With Ultrasound-Determined Carotid Atherosclerotic Plaque Instability
por: Wang, Yu, et al.
Publicado: (2021)

Serum YKL-40 Levels Are Associated with the Atherogenic Index of Plasma in Children
por: Kwon, Yoowon, et al.
Publicado: (2020)

YKL-40 - an emerging biomarker in cardiovascular disease and diabetes
por: Rathcke, Camilla N, et al.
Publicado: (2009)

Serum YKL-40 Levels in Patients with Gastric Cancer
por: Itik, Veyis, et al.
Publicado: (2011)

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias
por: Llorens, Franc, et al.
Publicado: (2017)

YKL-40 as a possible marker of neutrophilic asthma
por: Specjalski, Krzysztof, et al.
Publicado: (2023)

YKL-40 and the Cellular Metabolic Profile in Parkinson’s Disease
por: Gevezova, Maria, et al.
Publicado: (2023)

Prognostic value of YKL-40 in colorectal carcinoma patients: A meta-analysis
por: Wang, Jian, et al.
Publicado: (2022)

Circulating YKL-40 Level, but not CHI3L1 Gene Variants, Is Associated with Atherosclerosis-Related Quantitative Traits and the Risk of Peripheral Artery Disease
por: Wu, Semon, et al.
Publicado: (2014)

Increased YKL-40 levels are linked with disease severity of initially diagnosed Graves’ disease
por: Chen, Yi-Ding, et al.
Publicado: (2023)

Usefulness of Plasma YKL-40 in Management of Community-Acquired Pneumonia Severity in Patients
por: Wang, Hsiang-Ling, et al.
Publicado: (2013)

Elevation of YKL-40 in the CSF of Anti-NMDAR Encephalitis Patients Is Associated With Poor Prognosis
por: Chen, Jinyu, et al.
Publicado: (2018)

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis
por: Shao, Rong, et al.
Publicado: (2009)

YKL-40 acts as an angiogenic factor to promote tumor angiogenesis
por: Shao, Rong
Publicado: (2013)

Cerebrospinal fluid neurogranin and YKL‐40 as biomarkers of Alzheimer's disease
por: Janelidze, Shorena, et al.
Publicado: (2015)

Prognosis and Reclassification by YKL‐40 in Stable Coronary Artery Disease
por: Schroder, Jakob, et al.
Publicado: (2020)

Effect of Vitamin D on YKL-40: Rat Hypercholesterolemia Model
por: Kocabas, Rahim
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s0g918g659hfsc5s9bnlvpqfom