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Screening for effective cell-penetrating peptides with minimal impact on epithelial cells and gut commensals in vitro

One of the biggest challenges for oral drug absorption is the epithelial barrier of the gastrointestinal tract. The use of cell-penetrating peptides (CPPs) to modulate the epithelial barrier function is known to be an effective strategy to improve drug absorption and bioavailability. In this study w...

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Detalles Bibliográficos
Autores principales: Gelli, Hitesh P., Vazquez-Uribe, Ruben, Sommer, Morten Otto Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666501/
https://www.ncbi.nlm.nih.gov/pubmed/36408245
http://dx.doi.org/10.3389/fphar.2022.1049324