Cargando…

Maternal childhood trauma is associated with offspring body size during the first year of life

Maternal childhood trauma (MCT) is an important factor affecting offspring size at birth. Whether the effect of MCT persists during the subsequent development remains unclear. We present the results of a semi-longitudinal investigation examining the physical growth of infants born to mothers with hi...

Descripción completa

Detalles Bibliográficos
Autores principales: Apanasewicz, Anna, Danel, Dariusz P., Piosek, Magdalena, Wychowaniec, Patrycja, Babiszewska-Aksamit, Magdalena, Ziomkiewicz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666509/
https://www.ncbi.nlm.nih.gov/pubmed/36380091
http://dx.doi.org/10.1038/s41598-022-23740-6
_version_ 1784831522858074112
author Apanasewicz, Anna
Danel, Dariusz P.
Piosek, Magdalena
Wychowaniec, Patrycja
Babiszewska-Aksamit, Magdalena
Ziomkiewicz, Anna
author_facet Apanasewicz, Anna
Danel, Dariusz P.
Piosek, Magdalena
Wychowaniec, Patrycja
Babiszewska-Aksamit, Magdalena
Ziomkiewicz, Anna
author_sort Apanasewicz, Anna
collection PubMed
description Maternal childhood trauma (MCT) is an important factor affecting offspring size at birth. Whether the effect of MCT persists during the subsequent development remains unclear. We present the results of a semi-longitudinal investigation examining the physical growth of infants born to mothers with high (HCT) and low (LCT) childhood trauma during the first year of life. One hundred healthy mother-infant dyads were included based on following criteria: exclusive breastfeeding, birth on term with appropriate weight for gestational age. MCT was assessed using the Early Life Stress Questionnaire. The weight, length, and head circumference of the infant were taken at birth, 5 and 12 months postpartum. Separate MANCOVA models were run for infant size at each age. We found an association between MCT and infant size at 5 and 12 months. The children of mothers with HCT had higher weight and greater head circumference than the children of mothers with LCT. These results suggest that MCT might contribute to developmental programming of offspring growth during the first year of life. From an evolutionary perspective, the larger size of HCT mother's offspring might represent an adaptation to potentially harsh environmental conditions. This effect might be mediated by epigenetic changes to DNA and altered breast milk composition.
format Online
Article
Text
id pubmed-9666509
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-96665092022-11-17 Maternal childhood trauma is associated with offspring body size during the first year of life Apanasewicz, Anna Danel, Dariusz P. Piosek, Magdalena Wychowaniec, Patrycja Babiszewska-Aksamit, Magdalena Ziomkiewicz, Anna Sci Rep Article Maternal childhood trauma (MCT) is an important factor affecting offspring size at birth. Whether the effect of MCT persists during the subsequent development remains unclear. We present the results of a semi-longitudinal investigation examining the physical growth of infants born to mothers with high (HCT) and low (LCT) childhood trauma during the first year of life. One hundred healthy mother-infant dyads were included based on following criteria: exclusive breastfeeding, birth on term with appropriate weight for gestational age. MCT was assessed using the Early Life Stress Questionnaire. The weight, length, and head circumference of the infant were taken at birth, 5 and 12 months postpartum. Separate MANCOVA models were run for infant size at each age. We found an association between MCT and infant size at 5 and 12 months. The children of mothers with HCT had higher weight and greater head circumference than the children of mothers with LCT. These results suggest that MCT might contribute to developmental programming of offspring growth during the first year of life. From an evolutionary perspective, the larger size of HCT mother's offspring might represent an adaptation to potentially harsh environmental conditions. This effect might be mediated by epigenetic changes to DNA and altered breast milk composition. Nature Publishing Group UK 2022-11-15 /pmc/articles/PMC9666509/ /pubmed/36380091 http://dx.doi.org/10.1038/s41598-022-23740-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Apanasewicz, Anna
Danel, Dariusz P.
Piosek, Magdalena
Wychowaniec, Patrycja
Babiszewska-Aksamit, Magdalena
Ziomkiewicz, Anna
Maternal childhood trauma is associated with offspring body size during the first year of life
title Maternal childhood trauma is associated with offspring body size during the first year of life
title_full Maternal childhood trauma is associated with offspring body size during the first year of life
title_fullStr Maternal childhood trauma is associated with offspring body size during the first year of life
title_full_unstemmed Maternal childhood trauma is associated with offspring body size during the first year of life
title_short Maternal childhood trauma is associated with offspring body size during the first year of life
title_sort maternal childhood trauma is associated with offspring body size during the first year of life
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666509/
https://www.ncbi.nlm.nih.gov/pubmed/36380091
http://dx.doi.org/10.1038/s41598-022-23740-6
work_keys_str_mv AT apanasewiczanna maternalchildhoodtraumaisassociatedwithoffspringbodysizeduringthefirstyearoflife
AT daneldariuszp maternalchildhoodtraumaisassociatedwithoffspringbodysizeduringthefirstyearoflife
AT piosekmagdalena maternalchildhoodtraumaisassociatedwithoffspringbodysizeduringthefirstyearoflife
AT wychowaniecpatrycja maternalchildhoodtraumaisassociatedwithoffspringbodysizeduringthefirstyearoflife
AT babiszewskaaksamitmagdalena maternalchildhoodtraumaisassociatedwithoffspringbodysizeduringthefirstyearoflife
AT ziomkiewiczanna maternalchildhoodtraumaisassociatedwithoffspringbodysizeduringthefirstyearoflife