Rapidly Progressive and Catastrophic Calciphylaxis After Mechanical Valve Replacement: An Anticoagulation Dilemma

Warfarin is the only approved anticoagulant after mechanical valve replacement, but it is a well described risk factor for calciphylaxis among patients with end-stage kidney disease. Our patient with end-stage kidney disease rapidly developed calciphylaxis after dual mechanical valve replacement in...

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Autores principales: Nyembo, Philippe F., Eidman, Keith E., Simegn, Mengistu, Shaffer, Andrew W., Shroff, Gautam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666739/
https://www.ncbi.nlm.nih.gov/pubmed/36406917
http://dx.doi.org/10.1016/j.jaccas.2022.07.034
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author Nyembo, Philippe F.
Eidman, Keith E.
Simegn, Mengistu
Shaffer, Andrew W.
Shroff, Gautam R.
author_facet Nyembo, Philippe F.
Eidman, Keith E.
Simegn, Mengistu
Shaffer, Andrew W.
Shroff, Gautam R.
author_sort Nyembo, Philippe F.
collection PubMed
description Warfarin is the only approved anticoagulant after mechanical valve replacement, but it is a well described risk factor for calciphylaxis among patients with end-stage kidney disease. Our patient with end-stage kidney disease rapidly developed calciphylaxis after dual mechanical valve replacement in association with warfarin initiation, posing significant challenges in clinical management and a fatal outcome. (Level of Difficulty: Intermediate.)
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spelling pubmed-96667392022-11-17 Rapidly Progressive and Catastrophic Calciphylaxis After Mechanical Valve Replacement: An Anticoagulation Dilemma Nyembo, Philippe F. Eidman, Keith E. Simegn, Mengistu Shaffer, Andrew W. Shroff, Gautam R. JACC Case Rep Case Report Warfarin is the only approved anticoagulant after mechanical valve replacement, but it is a well described risk factor for calciphylaxis among patients with end-stage kidney disease. Our patient with end-stage kidney disease rapidly developed calciphylaxis after dual mechanical valve replacement in association with warfarin initiation, posing significant challenges in clinical management and a fatal outcome. (Level of Difficulty: Intermediate.) Elsevier 2022-10-05 /pmc/articles/PMC9666739/ /pubmed/36406917 http://dx.doi.org/10.1016/j.jaccas.2022.07.034 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nyembo, Philippe F.
Eidman, Keith E.
Simegn, Mengistu
Shaffer, Andrew W.
Shroff, Gautam R.
Rapidly Progressive and Catastrophic Calciphylaxis After Mechanical Valve Replacement: An Anticoagulation Dilemma
title Rapidly Progressive and Catastrophic Calciphylaxis After Mechanical Valve Replacement: An Anticoagulation Dilemma
title_full Rapidly Progressive and Catastrophic Calciphylaxis After Mechanical Valve Replacement: An Anticoagulation Dilemma
title_fullStr Rapidly Progressive and Catastrophic Calciphylaxis After Mechanical Valve Replacement: An Anticoagulation Dilemma
title_full_unstemmed Rapidly Progressive and Catastrophic Calciphylaxis After Mechanical Valve Replacement: An Anticoagulation Dilemma
title_short Rapidly Progressive and Catastrophic Calciphylaxis After Mechanical Valve Replacement: An Anticoagulation Dilemma
title_sort rapidly progressive and catastrophic calciphylaxis after mechanical valve replacement: an anticoagulation dilemma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666739/
https://www.ncbi.nlm.nih.gov/pubmed/36406917
http://dx.doi.org/10.1016/j.jaccas.2022.07.034
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