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The New T Cell Subset Opens a New Realm for Tumor Immunotherapy
Immunotherapy with immune checkpoint inhibitors had achieved great success. However, only a subset of patients responds positively to these therapies. The latest study published on Nature by Chou and colleagues found a new T cell subset from tumor-infiltrating T cells which lack PD-1 on the cell sur...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666835/ https://www.ncbi.nlm.nih.gov/pubmed/36377088 http://dx.doi.org/10.1177/09636897221138037 |
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author | Zhu, Huanjin Zeng, Chong Wang, Weidong |
author_facet | Zhu, Huanjin Zeng, Chong Wang, Weidong |
author_sort | Zhu, Huanjin |
collection | PubMed |
description | Immunotherapy with immune checkpoint inhibitors had achieved great success. However, only a subset of patients responds positively to these therapies. The latest study published on Nature by Chou and colleagues found a new T cell subset from tumor-infiltrating T cells which lack PD-1 on the cell surface and potent cytotoxic activities against tumor cells. This finding provides a novel insight into the development of new therapies for tumors that do not respond to immune checkpoint blockade in the future. |
format | Online Article Text |
id | pubmed-9666835 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-96668352022-11-17 The New T Cell Subset Opens a New Realm for Tumor Immunotherapy Zhu, Huanjin Zeng, Chong Wang, Weidong Cell Transplant Editorial Immunotherapy with immune checkpoint inhibitors had achieved great success. However, only a subset of patients responds positively to these therapies. The latest study published on Nature by Chou and colleagues found a new T cell subset from tumor-infiltrating T cells which lack PD-1 on the cell surface and potent cytotoxic activities against tumor cells. This finding provides a novel insight into the development of new therapies for tumors that do not respond to immune checkpoint blockade in the future. SAGE Publications 2022-11-14 /pmc/articles/PMC9666835/ /pubmed/36377088 http://dx.doi.org/10.1177/09636897221138037 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Editorial Zhu, Huanjin Zeng, Chong Wang, Weidong The New T Cell Subset Opens a New Realm for Tumor Immunotherapy |
title | The New T Cell Subset Opens a New Realm for Tumor
Immunotherapy |
title_full | The New T Cell Subset Opens a New Realm for Tumor
Immunotherapy |
title_fullStr | The New T Cell Subset Opens a New Realm for Tumor
Immunotherapy |
title_full_unstemmed | The New T Cell Subset Opens a New Realm for Tumor
Immunotherapy |
title_short | The New T Cell Subset Opens a New Realm for Tumor
Immunotherapy |
title_sort | new t cell subset opens a new realm for tumor
immunotherapy |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666835/ https://www.ncbi.nlm.nih.gov/pubmed/36377088 http://dx.doi.org/10.1177/09636897221138037 |
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