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How much does the typical ecological meta‐analysis overestimate the true mean effect size?

Many primary research studies in ecology are underpowered, providing very imprecise estimates of effect size. Meta‐analyses partially mitigate this imprecision by combining data from different studies. But meta‐analytic estimates of mean effect size may still remain imprecise, particularly if the me...

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Autor principal: Fox, Jeremy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666907/
https://www.ncbi.nlm.nih.gov/pubmed/36407900
http://dx.doi.org/10.1002/ece3.9521
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author Fox, Jeremy W.
author_facet Fox, Jeremy W.
author_sort Fox, Jeremy W.
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description Many primary research studies in ecology are underpowered, providing very imprecise estimates of effect size. Meta‐analyses partially mitigate this imprecision by combining data from different studies. But meta‐analytic estimates of mean effect size may still remain imprecise, particularly if the meta‐analysis includes a small number of studies. Imprecise, large‐magnitude estimates of mean effect size from small meta‐analyses likely would shrink if additional studies were conducted (regression towards the mean). Here, I propose a way to estimate and correct this regression to the mean, using meta‐meta‐analysis (meta‐analysis of meta‐analyses). Hierarchical random effects meta‐meta‐analysis shrinks estimated mean effect sizes from different meta‐analyses towards the grand mean, bringing those estimated means closer on average to their unknown true values. The intuition is that, if a meta‐analysis reports a mean effect size much larger in magnitude than that reported by other meta‐analyses, that large mean effect size likely is an overestimate. This intuition holds even if different meta‐analyses of different topics have different true mean effect sizes. Drawing on a compilation of data from hundreds of ecological meta‐analyses, I find that the typical (median) ecological meta‐analysis overestimates the absolute magnitude of the true mean effect size by ~10%. Some small ecological meta‐analyses overestimate the magnitude of the true mean effect size by >50%. Meta‐meta‐analysis is a promising tool for improving the accuracy of meta‐analytic estimates of mean effect size, particularly estimates based on just a few studies.
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spelling pubmed-96669072022-11-17 How much does the typical ecological meta‐analysis overestimate the true mean effect size? Fox, Jeremy W. Ecol Evol Research Articles Many primary research studies in ecology are underpowered, providing very imprecise estimates of effect size. Meta‐analyses partially mitigate this imprecision by combining data from different studies. But meta‐analytic estimates of mean effect size may still remain imprecise, particularly if the meta‐analysis includes a small number of studies. Imprecise, large‐magnitude estimates of mean effect size from small meta‐analyses likely would shrink if additional studies were conducted (regression towards the mean). Here, I propose a way to estimate and correct this regression to the mean, using meta‐meta‐analysis (meta‐analysis of meta‐analyses). Hierarchical random effects meta‐meta‐analysis shrinks estimated mean effect sizes from different meta‐analyses towards the grand mean, bringing those estimated means closer on average to their unknown true values. The intuition is that, if a meta‐analysis reports a mean effect size much larger in magnitude than that reported by other meta‐analyses, that large mean effect size likely is an overestimate. This intuition holds even if different meta‐analyses of different topics have different true mean effect sizes. Drawing on a compilation of data from hundreds of ecological meta‐analyses, I find that the typical (median) ecological meta‐analysis overestimates the absolute magnitude of the true mean effect size by ~10%. Some small ecological meta‐analyses overestimate the magnitude of the true mean effect size by >50%. Meta‐meta‐analysis is a promising tool for improving the accuracy of meta‐analytic estimates of mean effect size, particularly estimates based on just a few studies. John Wiley and Sons Inc. 2022-11-15 /pmc/articles/PMC9666907/ /pubmed/36407900 http://dx.doi.org/10.1002/ece3.9521 Text en © 2022 The Author. Ecology and Evolution published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Fox, Jeremy W.
How much does the typical ecological meta‐analysis overestimate the true mean effect size?
title How much does the typical ecological meta‐analysis overestimate the true mean effect size?
title_full How much does the typical ecological meta‐analysis overestimate the true mean effect size?
title_fullStr How much does the typical ecological meta‐analysis overestimate the true mean effect size?
title_full_unstemmed How much does the typical ecological meta‐analysis overestimate the true mean effect size?
title_short How much does the typical ecological meta‐analysis overestimate the true mean effect size?
title_sort how much does the typical ecological meta‐analysis overestimate the true mean effect size?
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666907/
https://www.ncbi.nlm.nih.gov/pubmed/36407900
http://dx.doi.org/10.1002/ece3.9521
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