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Functional immunophenotyping of children with critical status asthmaticus identifies differential gene expression responses in neutrophils exposed to a poly(I:C) stimulus

The host immune response to a viral immune stimulus has not been examined in children during a life-threatening asthma attack. We determined whether we could identify clusters of children with critical asthma by functional immunophenotyping using an intracellular viral analog stimulus. We performed...

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Detalles Bibliográficos
Autores principales: Grunwell, Jocelyn R., Rad, Milad G., Stephenson, Susan T., Mohammad, Ahmad F., Opolka, Cydney, Fitzpatrick, Anne M., Kamaleswaran, Rishikesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666940/
https://www.ncbi.nlm.nih.gov/pubmed/36385161
http://dx.doi.org/10.1038/s41598-022-24261-y