Cargando…

Low-normal serum unconjugated bilirubin levels are associated with late but not early carotid atherosclerotic lesions in T2DM subjects

AIMS: We aimed to examine the association of serum unconjugated bilirubin (UCB) within normal limits with carotid atherosclerosis in Chinese patients with type 2 diabetes mellitus (T2DM). METHODS: This cross-sectional, real-world study was performed in 8,006 hospitalized T2DM patients including 4,15...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Chun-Hua, Wang, Jun-Wei, Ke, Jiang-Feng, Li, Jing-Bo, Li, Mei-Fang, Li, Lian-Xi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667095/ https://www.ncbi.nlm.nih.gov/pubmed/36407305 http://dx.doi.org/10.3389/fendo.2022.948338

Ejemplares similares

Fluorescent protein-based detection of unconjugated bilirubin in newborn serum
por: Iwatani, Sota, et al.
Publicado: (2016)

Serum Lipocalin-2 Levels Are Increased and Independently Associated With Early-Stage Renal Damage and Carotid Atherosclerotic Plaque in Patients With T2DM
por: Gan, Jing, et al.
Publicado: (2022)

Unconjugated bilirubin induces pyroptosis in cultured rat cortical astrocytes
por: Feng, Jie, et al.
Publicado: (2018)

Unconjugated Bilirubin Attenuates DSS-Induced Colitis Potentially via Enhancement of Bilirubin Reabsorption
por: Zhao, Chong, et al.
Publicado: (2021)

Revalidation and rationale for high pKa values of unconjugated bilirubin
por: Ostrow, J Donald, et al.
Publicado: (2007)

Evaluation of Treatment Thresholds for Unconjugated Hyperbilirubinemia in Preterm Infants: Effects on Serum Bilirubin and on Hearing Loss?
por: Hulzebos, Christian V., et al.
Publicado: (2013)

Unconjugated bilirubin ameliorates the inflammation and digestive protease increase in TNBS-induced colitis
por: Zhou, Jin-An, et al.
Publicado: (2017)

The Evolving Landscape of Neurotoxicity by Unconjugated Bilirubin: Role of Glial Cells and Inflammation
por: Brites, Dora
Publicado: (2012)

Unconjugated Bilirubin Exposure Impairs Hippocampal Long-Term Synaptic Plasticity
por: Chang, Fang-Yu, et al.
Publicado: (2009)

Neurotoxicity of Unconjugated Bilirubin in Neonatal Hypoxic-Ischemic Brain Injury in vitro
por: Dani, Carlo, et al.
Publicado: (2021)

Physico-chemical characterization of bilirubin-10-sulfonate and comparison of its acid–base behavior with unconjugated bilirubin
por: Čepa, Adam, et al.
Publicado: (2021)

Impact of voxelotor (GBT440) on unconjugated bilirubin and jaundice in sickle cell disease
por: Telfer, Paul, et al.
Publicado: (2018)

Unconjugated bilirubin alleviates experimental ulcerative colitis by regulating intestinal barrier function and immune inflammation
por: Zheng, Jia-Dong, et al.
Publicado: (2019)

Low-grade albuminuria is associated with early but not late carotid atherosclerotic lesions in community-based patients with type 2 diabetes
por: Li, Mei-Fang, et al.
Publicado: (2013)

Serum Bilirubin Level Is Increased in Metabolically Healthy Obesity
por: Fu, Jing, et al.
Publicado: (2022)

Exposure to Lipopolysaccharide and/or Unconjugated Bilirubin Impair the Integrity and Function of Brain Microvascular Endothelial Cells
por: Cardoso, Filipa L., et al.
Publicado: (2012)

Measuring endogenous levels of unconjugated bilirubin released from isolated murine brain tissue during oxygen-glucose deprivation
por: Liu, Han-Wei, et al.
Publicado: (2023)

Expression profiling of N6-methyladenosine-modified mRNA in PC12 cells in response to unconjugated bilirubin
por: Zhou, Jinfu, et al.
Publicado: (2023)

Low solubility of unconjugated bilirubin in dimethylsulfoxide – water systems: implications for pK(a) determinations
por: Mukerjee, Pasupati, et al.
Publicado: (2002)

Unconjugated Bilirubin exerts Pro-Apoptotic Effect on Platelets via p38-MAPK activation
por: NaveenKumar, Somanathapura K., et al.
Publicado: (2015)

Hyperbilirubinemia Maintained by Chronic Supplementation of Unconjugated Bilirubin Improves the Clinical Course of Experimental Autoimmune Arthritis
por: Sykora, Tomas, et al.
Publicado: (2021)

Interactions of unconjugated bilirubin with vesicles, cyclodextrins and micelles: New modeling and the role of high pKa values
por: Mukerjee, Pasupati, et al.
Publicado: (2010)

Time-dependent dual effects of high levels of unconjugated bilirubin on the human blood-brain barrier lining
por: Palmela, Inês, et al.
Publicado: (2012)

Relation between unconjugated bilirubin and RDW, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio in Gilbert’s syndrome
por: Sarlak, Hakan, et al.
Publicado: (2016)

Systematic Influence of Circulating Bilirubin Levels on Osteoporosis
por: Zhao, Jinqiu, et al.
Publicado: (2021)

UGT1A1 mutation association with increased bilirubin levels and severity of unconjugated hyperbilirubinemia in ABO incompatible newborns of China
por: Yang, Hui, et al.
Publicado: (2021)

Study on the Heterogeneity of T-DM1 and the Analysis of the Unconjugated Linker Structure under a Stable Conjugation Process
por: Wu, Guanghao, et al.
Publicado: (2019)

Relation Between Unconjugated Bilirubin and Peripheral Biomarkers of Inflammation Derived From Complete Blood Counts in Patients With Acute Stage of Schizophrenia
por: Xu, Haiting, et al.
Publicado: (2022)

Association of Serum Bilirubin With Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
por: Liang, Chen, et al.
Publicado: (2022)

High-normal serum bilirubin decreased the risk of lower limb atherosclerosis in type 2 diabetes: a real-world study
por: Zhao, Cui-Chun, et al.
Publicado: (2023)

Modulatory effect of filarial infection on the systemic hormone levels in subjects with metabolic syndrome (DM-LF5)
por: Sibi, Joy Manohar, et al.
Publicado: (2022)

Serum free triiodothyronine is inversely associated with diabetic peripheral neuropathy but not with carotid atherosclerotic lesions in euthyroid patients with type 2 diabetes
por: Li, Mei-Fang, et al.
Publicado: (2021)

A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells
por: Calligaris, Raffaella, et al.
Publicado: (2009)

Causal association between serum total bilirubin and cholelithiasis: a bidirectional two-sample Mendelian randomization study
por: Sun, Yang, et al.
Publicado: (2023)

Identification of potential biomarkers and pathways associated with carotid atherosclerotic plaques in type 2 diabetes mellitus: A transcriptomics study
por: Yu, Tian, et al.
Publicado: (2022)

Blood unconjugated bilirubin and tacrolimus are negative predictors of specific cellular immunity in kidney transplant recipients after SAR-CoV-2 inactivated vaccination
por: Zhang, Lei, et al.
Publicado: (2023)

Functional Induction of the Cystine-Glutamate Exchanger System X(c) (-) Activity in SH-SY5Y Cells by Unconjugated Bilirubin
por: Giraudi, Pablo J., et al.
Publicado: (2011)

Hydrophilic bile acids protect human blood-brain barrier endothelial cells from disruption by unconjugated bilirubin: an in vitro study
por: Palmela, Inês, et al.
Publicado: (2015)

A Perspective on a Possible Relation Between the Psychopathology of the Schizophrenia/Schizoaffective Spectrum and Unconjugated Bilirubin: A Longitudinal Protocol Study
por: Gama Marques, João, et al.
Publicado: (2018)

Klotho inversely relates with carotid intima- media thickness in atherosclerotic patients with normal renal function (eGFR ≥60 mL/min/1.73m(2)): a proof-of-concept study
por: Donate-Correa, Javier, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hoo9eqbq1vgqrmffeklf2fjaeo