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Stochastic behaviors of an improved Gompertz tumor growth model with coupled two types noise

In this work, an improved Gompertz tumor growth model has been introduced. The expressions of steady probability distributions (SPD) of stochastic Gompertz tumor growth models are studied by using the technique of Fokker-Planck equation (FPE), and their dynamic behaviors are also further investigate...

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Detalles Bibliográficos
Autores principales: Lv, Huijun, He, Guitian, Cheng, Hui, Peng, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667274/
https://www.ncbi.nlm.nih.gov/pubmed/36406688
http://dx.doi.org/10.1016/j.heliyon.2022.e11574
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author Lv, Huijun
He, Guitian
Cheng, Hui
Peng, Yun
author_facet Lv, Huijun
He, Guitian
Cheng, Hui
Peng, Yun
author_sort Lv, Huijun
collection PubMed
description In this work, an improved Gompertz tumor growth model has been introduced. The expressions of steady probability distributions (SPD) of stochastic Gompertz tumor growth models are studied by using the technique of Fokker-Planck equation (FPE), and their dynamic behaviors are also further investigated. Moreover, the expressions for mean, variance, skewness, as well as the mean first-passage time (MFPT) also have been derived. And the influence of noise intensity, correlation coefficient, and noise correlation time of SPD are further analyzed. It is worthy noting that the colored noise intensity has an important impact on SPD. Furthermore, adjusting birth and death parameters also significantly impact SPD, MFPT, mean, variance as well as skewness.
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spelling pubmed-96672742022-11-17 Stochastic behaviors of an improved Gompertz tumor growth model with coupled two types noise Lv, Huijun He, Guitian Cheng, Hui Peng, Yun Heliyon Research Article In this work, an improved Gompertz tumor growth model has been introduced. The expressions of steady probability distributions (SPD) of stochastic Gompertz tumor growth models are studied by using the technique of Fokker-Planck equation (FPE), and their dynamic behaviors are also further investigated. Moreover, the expressions for mean, variance, skewness, as well as the mean first-passage time (MFPT) also have been derived. And the influence of noise intensity, correlation coefficient, and noise correlation time of SPD are further analyzed. It is worthy noting that the colored noise intensity has an important impact on SPD. Furthermore, adjusting birth and death parameters also significantly impact SPD, MFPT, mean, variance as well as skewness. Elsevier 2022-11-11 /pmc/articles/PMC9667274/ /pubmed/36406688 http://dx.doi.org/10.1016/j.heliyon.2022.e11574 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Research Article
Lv, Huijun
He, Guitian
Cheng, Hui
Peng, Yun
Stochastic behaviors of an improved Gompertz tumor growth model with coupled two types noise
title Stochastic behaviors of an improved Gompertz tumor growth model with coupled two types noise
title_full Stochastic behaviors of an improved Gompertz tumor growth model with coupled two types noise
title_fullStr Stochastic behaviors of an improved Gompertz tumor growth model with coupled two types noise
title_full_unstemmed Stochastic behaviors of an improved Gompertz tumor growth model with coupled two types noise
title_short Stochastic behaviors of an improved Gompertz tumor growth model with coupled two types noise
title_sort stochastic behaviors of an improved gompertz tumor growth model with coupled two types noise
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667274/
https://www.ncbi.nlm.nih.gov/pubmed/36406688
http://dx.doi.org/10.1016/j.heliyon.2022.e11574
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