A human kidney and liver organoid‐based multi‐organ‐on‐a‐chip model to study the therapeutic effects and biodistribution of mesenchymal stromal cell‐derived extracellular vesicles

Mesenchymal stromal cell (MSC)‐derived small extracellular vesicles (sEVs) show therapeutic potential in multiple disease models, including kidney injury. Clinical translation of sEVs requires further preclinical and regulatory developments, including elucidation of the biodistribution and mode of a...

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Detalles Bibliográficos
Autores principales: Nguyen, Vivian V. T., Ye, Shicheng, Gkouzioti, Vasiliki, van Wolferen, Monique E., Yengej, Fjodor Yousef, Melkert, Dennis, Siti, Sofia, de Jong, Bart, Besseling, Paul J., Spee, Bart, van der Laan, Luc J. W., Horland, Reyk, Verhaar, Marianne C., van Balkom, Bas W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667402/
https://www.ncbi.nlm.nih.gov/pubmed/36382606
http://dx.doi.org/10.1002/jev2.12280

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