Interferon-λ treatment accelerates SARS-CoV-2 clearance despite age-related delays in the induction of T cell immunity

Interferons induced early after SARS-CoV-2 infection are crucial for shaping immunity and preventing severe COVID-19. We previously demonstrated that injection of pegylated interferon-lambda accelerated viral clearance in COVID-19 patients (NCT04354259). To determine if the viral decline is mediated...

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Detalles Bibliográficos
Autores principales: Santer, Deanna M., Li, Daniel, Ghosheh, Yanal, Zahoor, Muhammad Atif, Prajapati, Dhanvi, Hansen, Bettina E., Tyrrell, D. Lorne J., Feld, Jordan J., Gehring, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667439/
https://www.ncbi.nlm.nih.gov/pubmed/36385011
http://dx.doi.org/10.1038/s41467-022-34709-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667439/
https://www.ncbi.nlm.nih.gov/pubmed/36385011
http://dx.doi.org/10.1038/s41467-022-34709-4

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