Cargando…

A Coarse-Grained Molecular Dynamics Description of Docetaxel-Conjugate Release from PLGA Matrices

[Image: see text] Despite the extensive use of poly-lactic-glycolic-acid (PLGA) in biomedical applications, computational research on the mesoscopic characterization of PLGA-based delivery systems is limited. In this study, a computational model for PLGA is proposed, developed, and validated for the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pannuzzo, Martina, Felici, Alessia, Decuzzi, Paolo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667470/ https://www.ncbi.nlm.nih.gov/pubmed/36237166 http://dx.doi.org/10.1021/acs.biomac.2c00903

Ejemplares similares

Multiconfigurational Coarse-Grained Molecular Dynamics
por: Sharp, Morris E., et al.
Publicado: (2019)

Predicting the Miscibility and Rigidity of Poly(lactic-co-glycolic acid)/Polyethylene Glycol Blends via Molecular Dynamics Simulations
por: Pannuzzo, Martina, et al.
Publicado: (2020)

Coarse-Grained Descriptions of Dynamics for Networks with Both Intrinsic and Structural Heterogeneities
por: Bertalan, Tom, et al.
Publicado: (2017)

Towards design of drugs and delivery systems with the Martini coarse-grained model
por: Kjølbye, Lisbeth R., et al.
Publicado: (2022)

Molecular dynamics trajectories for 630 coarse-grained drug-membrane permeations
por: Hoffmann, Christian, et al.
Publicado: (2020)

Coarse-Grained Models Reveal Functional Dynamics – II. Molecular Dynamics Simulation at the Coarse-Grained Level – Theories and Biological Applications
por: Chng, Choon-Peng, et al.
Publicado: (2008)

Coarse-graining of the dynamics seen in neural networks
por: Ben-Tal, Alona, et al.
Publicado: (2013)

Coarse-Grained Molecular Dynamics Modelling of a Magnetic Polymersome
por: Ryzhkov, Aleksandr, et al.
Publicado: (2018)

Machine Learning of Coarse-Grained Molecular Dynamics Force Fields
por: Wang, Jiang, et al.
Publicado: (2019)

Coarse-Grained Molecular Dynamics of pH-Sensitive Lipids
por: Lado-Touriño, Isabel, et al.
Publicado: (2023)

Predicting Lipid Eutectics Using Coarse-Grained Molecular Dynamics
por: Cordina, Robert J., et al.
Publicado: (2023)

Surface modification of PLGA nanoparticles via human serum albumin conjugation for controlled delivery of docetaxel
por: Manoochehri, Saeed, et al.
Publicado: (2013)

Transferrin-Conjugated Docetaxel–PLGA Nanoparticles for Tumor Targeting: Influence on MCF-7 Cell Cycle
por: Jose, Sajan, et al.
Publicado: (2019)

Coarse-Grained Clustering Dynamics of Heterogeneously Coupled Neurons
por: Moon, Sung Joon, et al.
Publicado: (2015)

Coarse Grained Molecular Dynamics Simulations of Transmembrane Protein-Lipid Systems
por: Spijker, Peter, et al.
Publicado: (2010)

Coarse-Grained Modeling and Molecular Dynamics Simulations of Ca(2+)-Calmodulin
por: Nde, Jules, et al.
Publicado: (2021)

Theory and Practice of Coarse-Grained Molecular Dynamics of Biologically Important Systems
por: Liwo, Adam, et al.
Publicado: (2021)

Reactive Martini: Chemical Reactions in Coarse-Grained Molecular Dynamics Simulations
por: Sami, Selim, et al.
Publicado: (2023)

A Comparison of Hepatocyte Cytotoxic Mechanisms for Docetaxel and PLGA-Docetaxel Nanoparticls
por: Daraei, Bahram, et al.
Publicado: (2017)

Management of osteoarthritis: From drug molecules to nano/micromedicines
por: Di Francesco, Martina, et al.
Publicado: (2022)

Introducing Memory in Coarse-Grained Molecular Simulations
por: Klippenstein, Viktor, et al.
Publicado: (2021)

Coarse-Graining Protein Structures With Local Multivariate Features from Molecular Dynamics
por: Zhang, Zhiyong, et al.
Publicado: (2008)

A Generic Force Field for Protein Coarse-Grained Molecular Dynamics Simulation
por: Gu, Junfeng, et al.
Publicado: (2012)

Capturing RNA Folding Free Energy with Coarse-Grained Molecular Dynamics Simulations
por: Bell, David R., et al.
Publicado: (2017)

Coarse-graining molecular dynamics: stochastic models with non-Gaussian force distributions
por: Erban, Radek
Publicado: (2019)

The kinetic landscape of nucleosome assembly: A coarse-grained molecular dynamics study
por: Brandani, Giovanni B., et al.
Publicado: (2021)

Constant pH Coarse-Grained Molecular Dynamics with Stochastic Charge Neutralization
por: van Teijlingen, Alexander, et al.
Publicado: (2022)

A coarse-grained approach to model the dynamics of the actomyosin cortex
por: Hernández-del-Valle, Miguel, et al.
Publicado: (2022)

A coarse-grained model of the expansion of the human rhinovirus 2 capsid reveals insights in genome release
por: Indelicato, Giuliana, et al.
Publicado: (2019)

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile
por: Rafiei, Pedram, et al.
Publicado: (2017)

Coarse-grained description of the spatio-temporal dynamics of network activity from experimentally verified single-neuron models and connectivity
por: Fermani, Francesco, et al.
Publicado: (2015)

Coarse Grained Parallel Function Evaluation
por: Rulon, P, et al.
Publicado: (1992)

Chaos and coarse graining in statistical mechanics
por: Castiglione, Patrizia, et al.
Publicado: (2008)

The power of coarse graining in biomolecular simulations
por: Ingólfsson, Helgi I, et al.
Publicado: (2014)

Thermodynamics of the Coarse-Graining Master Equation
por: Schaller, Gernot, et al.
Publicado: (2020)

De Sitter stability and coarse graining
por: Markkanen, T.
Publicado: (2018)

Combining Coarse-Grained Protein Models with Replica-Exchange All-Atom Molecular Dynamics
por: Wabik, Jacek, et al.
Publicado: (2013)

Partial Unwrapping and Histone Tail Dynamics in Nucleosome Revealed by Coarse-Grained Molecular Simulations
por: Kenzaki, Hiroo, et al.
Publicado: (2015)

Mapping Cholesterol Interaction Sites on Serotonin Transporter through Coarse-Grained Molecular Dynamics
por: Ferraro, Mariarosaria, et al.
Publicado: (2016)

The Effect of Tethers on Artificial Cell Membranes: A Coarse-Grained Molecular Dynamics Study
por: Hoiles, William, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_j5ii2uqd6jitrgapc9hh8tot0m