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Modulation of the activity of histone lysine methyltransferases and demethylases by curcumin analog in leukaemia cells

Curcumin is a known epigenetic modifier that demonstrated antitumor effect in different types of cancer. The poor solubility and metabolic stability are major drawbacks that limit its development as an antitumor agent. Dimethoxycurcumin (DMC) is a more soluble and stable curcumin analog. In this stu...

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Detalles Bibliográficos
Autores principales: Sawesi, Suhila, Malkaram, Sridhar A., Abd Elmageed, Zakaria Y., Fandy, Tamer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667515/
https://www.ncbi.nlm.nih.gov/pubmed/36300880
http://dx.doi.org/10.1111/jcmm.17589