Ferroptosis in tumor immunity and therapy

Ferroptosis is a type of regulated cell death (RCD), and it plays an important role in the occurrence of diseases, especially the development of tumors. Ferroptosis of tumor cells affects the antitumor immunity and the immune response to treatment to varying degrees. Ferroptosis also plays a key rol...

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Detalles Bibliográficos
Autores principales: Gong, Chuandong, Ji, Qiankun, Wu, Miaojing, Tu, Zewei, Lei, Kunjian, Luo, Min, Liu, Junzhe, Lin, Li, Li, Kuangxun, Li, Jingying, Huang, Kai, Zhu, Xingen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667519/
https://www.ncbi.nlm.nih.gov/pubmed/36317423
http://dx.doi.org/10.1111/jcmm.17529
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author Gong, Chuandong
Ji, Qiankun
Wu, Miaojing
Tu, Zewei
Lei, Kunjian
Luo, Min
Liu, Junzhe
Lin, Li
Li, Kuangxun
Li, Jingying
Huang, Kai
Zhu, Xingen
author_facet Gong, Chuandong
Ji, Qiankun
Wu, Miaojing
Tu, Zewei
Lei, Kunjian
Luo, Min
Liu, Junzhe
Lin, Li
Li, Kuangxun
Li, Jingying
Huang, Kai
Zhu, Xingen
author_sort Gong, Chuandong
collection PubMed
description Ferroptosis is a type of regulated cell death (RCD), and it plays an important role in the occurrence of diseases, especially the development of tumors. Ferroptosis of tumor cells affects the antitumor immunity and the immune response to treatment to varying degrees. Ferroptosis also plays a key role in immune cells. This review outlines the mechanism of the immune‐related effects of ferroptosis pathways in tumor progression and treatment, and it discusses potential methods for improving antitumor immunity and enhancing the efficacy of current cancer treatments by targeting ferroptosis.
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spelling pubmed-96675192022-11-17 Ferroptosis in tumor immunity and therapy Gong, Chuandong Ji, Qiankun Wu, Miaojing Tu, Zewei Lei, Kunjian Luo, Min Liu, Junzhe Lin, Li Li, Kuangxun Li, Jingying Huang, Kai Zhu, Xingen J Cell Mol Med Review Ferroptosis is a type of regulated cell death (RCD), and it plays an important role in the occurrence of diseases, especially the development of tumors. Ferroptosis of tumor cells affects the antitumor immunity and the immune response to treatment to varying degrees. Ferroptosis also plays a key role in immune cells. This review outlines the mechanism of the immune‐related effects of ferroptosis pathways in tumor progression and treatment, and it discusses potential methods for improving antitumor immunity and enhancing the efficacy of current cancer treatments by targeting ferroptosis. John Wiley and Sons Inc. 2022-11-01 2022-11 /pmc/articles/PMC9667519/ /pubmed/36317423 http://dx.doi.org/10.1111/jcmm.17529 Text en © 2022 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Gong, Chuandong
Ji, Qiankun
Wu, Miaojing
Tu, Zewei
Lei, Kunjian
Luo, Min
Liu, Junzhe
Lin, Li
Li, Kuangxun
Li, Jingying
Huang, Kai
Zhu, Xingen
Ferroptosis in tumor immunity and therapy
title Ferroptosis in tumor immunity and therapy
title_full Ferroptosis in tumor immunity and therapy
title_fullStr Ferroptosis in tumor immunity and therapy
title_full_unstemmed Ferroptosis in tumor immunity and therapy
title_short Ferroptosis in tumor immunity and therapy
title_sort ferroptosis in tumor immunity and therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667519/
https://www.ncbi.nlm.nih.gov/pubmed/36317423
http://dx.doi.org/10.1111/jcmm.17529
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