Monte Carlo simulation of linac using PRIMO

BACKGROUND: Monte Carlo simulation is considered as the most accurate method for dose calculation in radiotherapy. PRIMO is a Monte-Carlo program with a user-friendly graphical interface. MATERIAL AND METHOD: A VitalBeam with 6MV and 6MV flattening filter free (FFF), equipped with the 120 Millennium multileaf collimator was simulated by PRIMO. We adjusted initial energy, energy full width at half maximum (FWHM), focal spot FWHM, and beam divergence to match the measurements. The water tank and ion-chamber were used in the measurement. Percentage depth dose (PDD) and off axis ratio (OAR) were evaluated with gamma passing rates (GPRs) implemented in PRIMO. PDDs were matched at different widths of standard square fields. OARs were matched at five depths. Transmission factor and dose leaf gap (DLG) were simulated. DLG was measured by electronic portal imaging device using a sweeping gap method. RESULT: For the criterion of 2%/2 mm, 1%/2 mm and 1%/1 mm, the GPRs of 6MV PDD were 99.33–100%, 99–100%, and 99–100%, respectively; the GPRs of 6MV FFF PDD were 99.33–100%, 98.99–99.66%, and 97.64–98.99%, respectively; the GPRs of 6MV OAR were 96.4–100%, 90.99–100%, and 85.12–98.62%, respectively; the GPRs of 6MV FFF OAR were 95.15–100%, 89.32–100%, and 87.02–99.74%, respectively. The calculated DLG matched well with the measurement (6MV: 1.36 mm vs. 1.41 mm; 6MV FFF: 1.07 mm vs. 1.03 mm, simulation vs measurement). The transmission factors were similar (6MV: 1.25% vs. 1.32%; 6MV FFF: 0.8% vs. 1.12%, simulation vs measurement). CONCLUSION: The calculated PDD, OAR, DLG and transmission factor were all in good agreement with measurements. PRIMO is an independent (with respect to analytical dose calculation algorithm) and accurate Monte Carlo tool. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13014-022-02149-5.