Cargando…

Insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report

BACKGROUND: The supra-acetabulum is a common site for malignant bone tumors, which can be difficult to differentiate from insufficiency fractures. We report a rare case of a stress fracture of the supra-acetabulum that required differentiation from a malignant bone tumor. CASE PRESENTATION: A 74-yea...

Descripción completa

Detalles Bibliográficos
Autores principales: Morinaga, Sei, Yamamoto, Norio, Hayashi, Katsuhiro, Takeuchi, Akihiko, Miwa, Shinji, Igarashi, Kentaro, Yonezawa, Hirotaka, Asano, Yohei, Saito, Shiro, Tsuchiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667604/
https://www.ncbi.nlm.nih.gov/pubmed/36380361
http://dx.doi.org/10.1186/s13256-022-03642-x
_version_ 1784831756367560704
author Morinaga, Sei
Yamamoto, Norio
Hayashi, Katsuhiro
Takeuchi, Akihiko
Miwa, Shinji
Igarashi, Kentaro
Yonezawa, Hirotaka
Asano, Yohei
Saito, Shiro
Tsuchiya, Hiroyuki
author_facet Morinaga, Sei
Yamamoto, Norio
Hayashi, Katsuhiro
Takeuchi, Akihiko
Miwa, Shinji
Igarashi, Kentaro
Yonezawa, Hirotaka
Asano, Yohei
Saito, Shiro
Tsuchiya, Hiroyuki
author_sort Morinaga, Sei
collection PubMed
description BACKGROUND: The supra-acetabulum is a common site for malignant bone tumors, which can be difficult to differentiate from insufficiency fractures. We report a rare case of a stress fracture of the supra-acetabulum that required differentiation from a malignant bone tumor. CASE PRESENTATION: A 74-year-old Japanese man presented to the hospital because of right hip joint pain. X-rays showed no obvious abnormalities. Magnetic resonance imaging showed an abnormality in the right supra-acetabulum, and he was referred to our department. A linear, low-signal region and its surrounding equal signal region were observed at the same site in the T1-weighted image, and a linear low-signal region and high signal region were observed in the surrounding area in the T2-weighted image. On the contrast-enhanced magnetic resonance imaging, the lesion was still unclear and the whole area was gradually enhanced. A computed tomography-guided needle biopsy was performed, but no tumor cells were observed, therefore the lesion was presumed to be a fracture healing. The bone density was 66% for the lumbar spine (young adult mean, L2–4), and blood biochemistry showed an increase in alkaline phosphatase and total type I procollagen N-terminal propeptide. CONCLUSION: This case was diagnosed as an insufficiency fracture of the supra-acetabulum in a male patient with primary osteoporosis by biopsy specimen. Initially, a pathological fracture associated with a malignant lesion was considered. On magnetic resonance imaging, the boundary around the fracture line was unclear and a signal change that was gradually enhanced by gadolinium was observed. This is likely to be bone marrow edema associated with the stress fracture, and we believe this to be a useful finding that may help in differentiating a stress fracture from a pathological fracture secondary to a malignant lesion.
format Online
Article
Text
id pubmed-9667604
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-96676042022-11-17 Insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report Morinaga, Sei Yamamoto, Norio Hayashi, Katsuhiro Takeuchi, Akihiko Miwa, Shinji Igarashi, Kentaro Yonezawa, Hirotaka Asano, Yohei Saito, Shiro Tsuchiya, Hiroyuki J Med Case Rep Case Report BACKGROUND: The supra-acetabulum is a common site for malignant bone tumors, which can be difficult to differentiate from insufficiency fractures. We report a rare case of a stress fracture of the supra-acetabulum that required differentiation from a malignant bone tumor. CASE PRESENTATION: A 74-year-old Japanese man presented to the hospital because of right hip joint pain. X-rays showed no obvious abnormalities. Magnetic resonance imaging showed an abnormality in the right supra-acetabulum, and he was referred to our department. A linear, low-signal region and its surrounding equal signal region were observed at the same site in the T1-weighted image, and a linear low-signal region and high signal region were observed in the surrounding area in the T2-weighted image. On the contrast-enhanced magnetic resonance imaging, the lesion was still unclear and the whole area was gradually enhanced. A computed tomography-guided needle biopsy was performed, but no tumor cells were observed, therefore the lesion was presumed to be a fracture healing. The bone density was 66% for the lumbar spine (young adult mean, L2–4), and blood biochemistry showed an increase in alkaline phosphatase and total type I procollagen N-terminal propeptide. CONCLUSION: This case was diagnosed as an insufficiency fracture of the supra-acetabulum in a male patient with primary osteoporosis by biopsy specimen. Initially, a pathological fracture associated with a malignant lesion was considered. On magnetic resonance imaging, the boundary around the fracture line was unclear and a signal change that was gradually enhanced by gadolinium was observed. This is likely to be bone marrow edema associated with the stress fracture, and we believe this to be a useful finding that may help in differentiating a stress fracture from a pathological fracture secondary to a malignant lesion. BioMed Central 2022-11-16 /pmc/articles/PMC9667604/ /pubmed/36380361 http://dx.doi.org/10.1186/s13256-022-03642-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Morinaga, Sei
Yamamoto, Norio
Hayashi, Katsuhiro
Takeuchi, Akihiko
Miwa, Shinji
Igarashi, Kentaro
Yonezawa, Hirotaka
Asano, Yohei
Saito, Shiro
Tsuchiya, Hiroyuki
Insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report
title Insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report
title_full Insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report
title_fullStr Insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report
title_full_unstemmed Insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report
title_short Insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report
title_sort insufficiency fracture of the supra-acetabulum that required differentiation from a pathological fracture secondary to a malignant bone tumor: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667604/
https://www.ncbi.nlm.nih.gov/pubmed/36380361
http://dx.doi.org/10.1186/s13256-022-03642-x
work_keys_str_mv AT morinagasei insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport
AT yamamotonorio insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport
AT hayashikatsuhiro insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport
AT takeuchiakihiko insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport
AT miwashinji insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport
AT igarashikentaro insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport
AT yonezawahirotaka insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport
AT asanoyohei insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport
AT saitoshiro insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport
AT tsuchiyahiroyuki insufficiencyfractureofthesupraacetabulumthatrequireddifferentiationfromapathologicalfracturesecondarytoamalignantbonetumoracasereport