Comparison of outcomes between flexible ureteroscopy and mini-percutaneous nephrolithotomy in the management of upper calyceal calculi larger than 2 cm

OBJECTIVE: To compare the outcomes of FURSL and m-PNL in the management of upper calyceal calculi larger than 2 cm. METHODS: A total of 75 patients with upper calyceal calculi larger than 2 cm that were treated by FURSL (n = 37) or mini-PNL (n = 38) were retrospectively analysed. The mean age, sex, stone burden, operative time, complications, length of hospitalization, and stone-free rate (SFR) were compared between the groups. The success of the procedure was defined by the absence of residual stones or residual fragments smaller than 4 mm on computed tomography at 4 weeks postoperatively. RESULTS: The two groups had comparable preoperative parameters. The mean operative time was significantly longer in the mini-PNL group than in the FURSL group (87.8 vs. 69.8 min, p < 0.001). The length of hospitalization was greater in the mini-PNL group than in the FURSL group (2.5 vs. 1.3 days, p < 0.001). Although the perioperative complication rate was higher in the mini-PNL group (23.7%) than in the FURSL group (13.5%), this difference was not statistically significant (p = 0.258). The SFR for the mini-PNL group was 89.5%, and that of the FURSL group was 81.1%; the difference was not significantly different (p = 0.304). CONCLUSIONS: Both FURSL and mini-PNL are effective and safe for the management of upper calyceal calculi larger than 2 cm. Of these two procedures, mini-PNL is less time consuming, FURSL is associated with faster recovery. FURSL can be considered a good alternative treatment in selected patients.