Neoantigen-specific TCR-T cell-based immunotherapy for acute myeloid leukemia

Neoantigens derived from non-synonymous somatic mutations are restricted to malignant cells and are thus considered ideal targets for T cell receptor (TCR)-based immunotherapy. Adoptive transfer of T cells bearing neoantigen-specific TCRs exhibits the ability to preferentially target tumor cells whi...

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Detalles Bibliográficos
Autores principales: Zhou, Weijun, Yu, Jinyi, Li, Yilu, Wang, Kankan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667632/
https://www.ncbi.nlm.nih.gov/pubmed/36384590
http://dx.doi.org/10.1186/s40164-022-00353-3

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