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New insights into epigenetic regulation of resistance to PD-1/PD-L1 blockade cancer immunotherapy: mechanisms and therapeutic opportunities

Programmed cell death protein 1(PD-1) is a type of immune-inhibitory checkpoint protein, which delivers inhibitory signals to cytotoxic T cells by binding to the programmed death ligand-1 (PD-L1) displayed on the surface of cancer cells. Antibodies blocking PD-1/PD-L1 interaction have been extensive...

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Detalles Bibliográficos
Autores principales:	Dai, Mengyuan, Liu, Miao, Yang, Hua, Küçük, Can, You, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667634/ https://www.ncbi.nlm.nih.gov/pubmed/36384676 http://dx.doi.org/10.1186/s40164-022-00356-0

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