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Genomic and transcriptomic analysis of a diffuse pleural mesothelioma patient-derived xenograft library

BACKGROUND: Diffuse pleural mesothelioma (DPM) is an aggressive malignancy that, despite recent treatment advances, has unacceptably poor outcomes. Therapeutic research in DPM is inhibited by a paucity of preclinical models that faithfully recapitulate the human disease. METHODS: We established 22 p...

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Detalles Bibliográficos
Autores principales:	Offin, Michael, Sauter, Jennifer L., Tischfield, Sam E., Egger, Jacklynn V., Chavan, Shweta, Shah, Nisargbhai S., Manoj, Parvathy, Ventura, Katia, Allaj, Viola, de Stanchina, Elisa, Travis, William, Ladanyi, Marc, Rimner, Andreas, Rusch, Valerie W., Adusumilli, Prasad S., Poirier, John T., Zauderer, Marjorie G., Rudin, Charles M., Sen, Triparna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667652/ https://www.ncbi.nlm.nih.gov/pubmed/36380343 http://dx.doi.org/10.1186/s13073-022-01129-4

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