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Relationships of APOE Genotypes With Small RNA and Protein Cargo of Brain Tissue Extracellular Vesicles From Patients With Late-Stage AD

BACKGROUND AND OBJECTIVES: Variants of the apolipoprotein E (APOE) gene are the greatest known risk factors for sporadic Alzheimer disease (AD). Three major APOE isoform alleles, ε2, ε3, and ε4, encode and produce proteins that differ by only 1–2 amino acids but have different binding partner intera...

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Detalles Bibliográficos
Autores principales:	Huang, Yiyao, Driedonks, Tom A.P., Cheng, Lesley, Rajapaksha, Harinda, Turchinovich, Andrey, Routenberg, David A., Nagaraj, Rajini, Redding-Ochoa, Javier, Arab, Tanina, Powell, Bonita H., Pletnikova, Olga, Troncoso, Juan C., Zheng, Lei, Hill, Andrew F., Mahairaki, Vasiliki, Witwer, Kenneth W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9667865/ https://www.ncbi.nlm.nih.gov/pubmed/36405397 http://dx.doi.org/10.1212/NXG.0000000000200026

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