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Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models

BACKGROUND: Glioblastoma multiforme (GBM) is the most malignant adult brain tumor. Current standard of care treatments have very limited efficacy, being the patients´ overall survival 14 months and the 2-year survival rate less than 10%. Therefore, the treatment of GBM is an urgent unmet clinical ne...

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Detalles Bibliográficos
Autores principales: Mancini, Andrea, Colapietro, Alessandro, Cristiano, Loredana, Rossetti, Alessandra, Mattei, Vincenzo, Gravina, Giovanni Luca, Perez-Montoyo, Héctor, Yeste-Velasco, Marc, Alfon, Jose, Domenech, Carles, Festuccia, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668006/
https://www.ncbi.nlm.nih.gov/pubmed/36408162
http://dx.doi.org/10.3389/fonc.2022.943064

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