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De novo pancytopaenia in an older adult with severe COVID-19 infection

During the COVID-19 pandemic, it was recognised that SARS-CoV-2 can cause multisystem illness. Non-respiratory complications observed early in the pandemic were haematological in nature. A rare but serious haematological complication of COVID-19 infection is pancytopaenia. We describe a case of an o...

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Autores principales: Lee, Helena, Thein, Onn Shaun, Muneer, Tazeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668033/
https://www.ncbi.nlm.nih.gov/pubmed/36379633
http://dx.doi.org/10.1136/bcr-2022-252609
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author Lee, Helena
Thein, Onn Shaun
Muneer, Tazeen
author_facet Lee, Helena
Thein, Onn Shaun
Muneer, Tazeen
author_sort Lee, Helena
collection PubMed
description During the COVID-19 pandemic, it was recognised that SARS-CoV-2 can cause multisystem illness. Non-respiratory complications observed early in the pandemic were haematological in nature. A rare but serious haematological complication of COVID-19 infection is pancytopaenia. We describe a case of an older adult without pre-existing haematological disease or risk factors for cell dyscrasia with severe pancytopaenia induced by COVID-19, who developed critical illness requiring respiratory support in intensive care and died. Our case report highlights that de novo pancytopaenia may only present with mild dermatological manifestations and may indicate severe COVID-19 infection. Management is primarily supportive and early involvement of haematology should be sought.
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spelling pubmed-96680332022-11-17 De novo pancytopaenia in an older adult with severe COVID-19 infection Lee, Helena Thein, Onn Shaun Muneer, Tazeen BMJ Case Rep Case Reports: Unusual presentation of more common disease/injury During the COVID-19 pandemic, it was recognised that SARS-CoV-2 can cause multisystem illness. Non-respiratory complications observed early in the pandemic were haematological in nature. A rare but serious haematological complication of COVID-19 infection is pancytopaenia. We describe a case of an older adult without pre-existing haematological disease or risk factors for cell dyscrasia with severe pancytopaenia induced by COVID-19, who developed critical illness requiring respiratory support in intensive care and died. Our case report highlights that de novo pancytopaenia may only present with mild dermatological manifestations and may indicate severe COVID-19 infection. Management is primarily supportive and early involvement of haematology should be sought. BMJ Publishing Group 2022-11-15 /pmc/articles/PMC9668033/ /pubmed/36379633 http://dx.doi.org/10.1136/bcr-2022-252609 Text en © BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.
spellingShingle Case Reports: Unusual presentation of more common disease/injury
Lee, Helena
Thein, Onn Shaun
Muneer, Tazeen
De novo pancytopaenia in an older adult with severe COVID-19 infection
title De novo pancytopaenia in an older adult with severe COVID-19 infection
title_full De novo pancytopaenia in an older adult with severe COVID-19 infection
title_fullStr De novo pancytopaenia in an older adult with severe COVID-19 infection
title_full_unstemmed De novo pancytopaenia in an older adult with severe COVID-19 infection
title_short De novo pancytopaenia in an older adult with severe COVID-19 infection
title_sort de novo pancytopaenia in an older adult with severe covid-19 infection
topic Case Reports: Unusual presentation of more common disease/injury
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668033/
https://www.ncbi.nlm.nih.gov/pubmed/36379633
http://dx.doi.org/10.1136/bcr-2022-252609
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