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Acceleration of Mesenchymal-to-Epithelial Transition (MET) during Direct Reprogramming Using Natural Compounds

Induced pluripotent stem cells (iPSCs) can be generated from somatic cells using Oct4, Sox2, Klf4, and c-Myc (OSKM). Small molecules can enhance reprogramming. Licochalcone D (LCD), a flavonoid compound present mainly in the roots of Glycyrrhiza inflata, acts on known signaling pathways involved in...

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Detalles Bibliográficos
Autores principales: Seo, Ji-Hye, Jang, Si Won, Jeon, Young-Joo, Eun, So Young, Hong, Yean Ju, Do, Jeong Tae, Chae, Jung-il, Choi, Hyun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Microbiology and Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668095/
https://www.ncbi.nlm.nih.gov/pubmed/36224763
http://dx.doi.org/10.4014/jmb.2208.08042

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