Cargando…

Genetic ablation of metabotropic glutamate receptor 5 in rats results in an autism-like behavioral phenotype

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in communication, and social skills, as well as repetitive and/or restrictive interests and behaviors. The severity of ASD varies from mild to severe, drastically interfering with the quality of life of affecte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eshraghi, Adrien A., Memis, Idil, Wang, Florence, White, Isaiah, Furar, Emily, Mittal, Jeenu, Moosa, Moeed, Atkins, Coleen M., Mittal, Rahul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668160/ https://www.ncbi.nlm.nih.gov/pubmed/36383609 http://dx.doi.org/10.1371/journal.pone.0275937

Ejemplares similares

Altered Blood Brain Barrier Permeability and Oxidative Stress in Cntnap2 Knockout Rat Model
por: Memis, Idil, et al.
Publicado: (2022)

Quality of Life, Neurosensory Disorders and Co-Occurring Medical Conditions in Individuals on the Spectrum, with a Special Focus on Females Diagnosed with Autism: A Systematic Review
por: Davies, Camron, et al.
Publicado: (2023)

Efficacy of coping mechanisms used during COVID-19 as reported by parents of children with autism
por: Wang, Florence, et al.
Publicado: (2023)

Recent advancements in noninvasive brain modulation for individuals with autism spectrum disorder
por: Griff, Jessica R., et al.
Publicado: (2022)

Modulation of Gut Microbiome as a Therapeutic Modality for Auditory Disorders
por: Godur, Dimitri A., et al.
Publicado: (2023)

Epigenetics and Autism Spectrum Disorder: Is There a Correlation?
por: Eshraghi, Adrien A., et al.
Publicado: (2018)

Implications of parental stress on worsening of behavioral problems in children with autism during COVID-19 pandemic: “the spillover hypothesis”
por: Eshraghi, Adrien A., et al.
Publicado: (2022)

The impact of COVID-19 on individuals with ASD in the US: Parent perspectives on social and support concerns
por: Furar, Emily, et al.
Publicado: (2022)

Recent advancements toward gapless neural-electrode interface post-cochlear implantation
por: Li, Crystal Y., et al.
Publicado: (2021)

Genotype-Phenotype Correlation for Predicting Cochlear Implant Outcome: Current Challenges and Opportunities
por: Eshraghi, Adrien A., et al.
Publicado: (2020)

Role of Cyclic Nucleotide Phosphodiesterases in Inner Ear and Hearing
por: Mittal, Rahul, et al.
Publicado: (2017)

Evaluating the Efficacy of Taurodeoxycholic Acid in Providing Otoprotection Using an in vitro Model of Electrode Insertion Trauma
por: Shah, Viraj, et al.
Publicado: (2020)

Central Auditory Processing Disorders in Individuals with Autism Spectrum Disorders
por: Ocak, Emre, et al.
Publicado: (2018)

Recent advancements in cell-based models for auditory disorders
por: Langlie, Jake, et al.
Publicado: (2022)

Unraveling pathological mechanisms in neurological disorders: the impact of cell-based and organoid models
por: Langlie, Jake, et al.
Publicado: (2022)

Gut-Induced Inflammation during Development May Compromise the Blood-Brain Barrier and Predispose to Autism Spectrum Disorder
por: Eshraghi, Rebecca S., et al.
Publicado: (2020)

The Outcomes of Cochlear Implantation in Usher Syndrome: A Systematic Review
por: Davies, Camron, et al.
Publicado: (2021)

COVID-19: overcoming the challenges faced by individuals with autism and their families
por: Eshraghi, Adrien A, et al.
Publicado: (2020)

Identification of Target Proteins Involved in Cochlear Hair Cell Progenitor Cytotoxicity following Gentamicin Exposure
por: Davies, Camron, et al.
Publicado: (2022)

The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism
por: Hadley, Dexter, et al.
Publicado: (2014)

Early Disruption of the Microbiome Leading to Decreased Antioxidant Capacity and Epigenetic Changes: Implications for the Rise in Autism
por: Eshraghi, Rebecca S., et al.
Publicado: (2018)

Biocompatibility of Bone Marrow-Derived Mesenchymal Stem Cells in the Rat Inner Ear following Trans-Tympanic Administration
por: Eshraghi, Adrien A., et al.
Publicado: (2020)

Metabotropic glutamate receptors inhibit microglial glutamate release
por: McMullan, Stephen M, et al.
Publicado: (2012)

Evaluating the Efficacy of L-N-acetylcysteine and Dexamethasone in Combination to Provide Otoprotection for Electrode Insertion Trauma
por: Eshraghi, Adrien A., et al.
Publicado: (2020)

Optical Control of Metabotropic Glutamate Receptors
por: Levitz, Joshua, et al.
Publicado: (2013)

Kinetic fingerprinting of metabotropic glutamate receptors
por: Kukaj, Taulant, et al.
Publicado: (2023)

Association of PRPS1 Mutations with Disease Phenotypes
por: Mittal, Rahul, et al.
Publicado: (2015)

Recent Advancements in the Regeneration of Auditory Hair Cells and Hearing Restoration
por: Mittal, Rahul, et al.
Publicado: (2017)

Therapeutic promise and principles: Metabotropic glutamate receptors
por: Maiese, Kenneth, et al.
Publicado: (2008)

Therapeutic Potential of Metabotropic Glutamate Receptor Modulators
por: Hovelsø, N, et al.
Publicado: (2012)

Homology modelling of metabotropic glutamate receptor 2
por: Mordalski, S, et al.
Publicado: (2011)

Metabotropic Glutamate Receptors for Parkinson's Disease Therapy
por: Gasparini, Fabrizio, et al.
Publicado: (2013)

Constitutive activity of metabotropic glutamate receptor 7
por: Kammermeier, Paul J
Publicado: (2015)

Metabotropic Glutamate Receptors and Interacting Proteins in Epileptogenesis
por: Qian, Feng, et al.
Publicado: (2016)

The Role of Metabotropic Glutamate Receptor Genes in Schizophrenia
por: Maj, Carlo, et al.
Publicado: (2016)

Special Issue on Metabotropic Glutamate Receptors: Editorial
por: Salt, Prof. Thomas E.
Publicado: (2016)

Structural Insights into Metabotropic Glutamate Receptor Activation
por: Koehl, Antoine, et al.
Publicado: (2019)

Role of Metabotropic Glutamate Receptors in Neurological Disorders
por: Crupi, Rosalia, et al.
Publicado: (2019)

Metabotropic glutamate receptor 5 in bulimia nervosa
por: Mihov, Yoan, et al.
Publicado: (2020)

Allosteric Molecular Switches in Metabotropic Glutamate Receptors
por: Orgován, Zoltán, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ftm9led47ngtv3tui9oqo20lsr