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Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling
Respiratory complex I is a ~1-MDa proton pump in mitochondria. Its structure has been revealed in great detail, but the structural basis of its assembly, in humans involving at least 15 assembly factors, is essentially unknown. We determined cryo–electron microscopy structures of assembly intermedia...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668296/ https://www.ncbi.nlm.nih.gov/pubmed/36383672 http://dx.doi.org/10.1126/sciadv.add3855 |